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Genistein is a variety of isoflavone which is most active, the product Genistein of our company is derived from dry and mature fruit of bean plant sophora Japonica. It is a pure and single element. It is a compound of heterocycle polyphenol.
Genistein can combine with estrogen receptor and have weak estrogen effect. So it is also called phytoestrogen. It is antagonistic to estrogen. It has protective effect or hormone related diseases. It can improve and prevent climacteric syndrome and osteoporosis. Genistein can serve as food supplement to be widely used in various healthy food for the middle-aged and old people.
Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.
Product Name: | Genistein | Part Used: | Fruit |
Latin Name: | Sophora japonica L. | Extract Solvent | Water&Ethanol |
ITEM | SPECIFICATION | TEST METHOD |
Physical Description |
Appearance | White or White Like Powder | Visual |
Odor | Characteristic | Organoleptic |
Taste | Characteristic | Olfactory |
Bulk Density | 50-60g/100ml | CP2015 |
Particle Size | 95%-99% through 80 mesh | CP2015 |
Chemical Tests |
Genistein | ≥98% | HPLC |
Loss on Drying | ≤1.0% | CP2015 (105 oC, 3 h) |
Ash | ≤1.0% | CP2015 |
Total Heavy Metals | ≤10 ppm | CP2015 |
Cadmium (Cd) | ≤1 ppm | CP2015(AAS) |
Mercury (Hg) | ≤1 ppm | CP2015(AAS) |
Lead (Pb) | ≤2 ppm | CP2015(AAS) |
Arsenic (As) | ≤2ppm | CP2015(AAS) |
Microbiology Control |
Aerobic Bacterial Count | ≤1,000 cfu/g | CP2015 |
Total Yeast & Mold | ≤100 cfu/g | CP2015 |
Escherichia Coli | Negative | CP2015 |
Salmonella | Negative | CP2015 |
Staphlococcus Aureus | Negative | CP2015 |
function
1.Genistein is a strong antioxidant. Genistein removes damaging free radicals and reduces lipid peroxidation.
2.Gensistein prevents the formation of hearth attacks and strokes by acting as anticlotting agent.
3.Genistein increases the activity of other antioxidant enzymes such as glutathione peroxidase, superoxide dismutase and
glutathione reductase.
4.Studies have shown that genistein can also influence the growth of cells which are not hormone-dependent.
5.Genistein seems to inhibit the activity of tyrosine kinase,which plays an important role in cell growth.
6.Reduction of tyrosine activity will result in a reduced cancer risk.
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