Diosmin

Product name: Diosmin

Synonym: Barosmin, Buchu resin, Daflon.

7-{[6-O-(Deoxy-α-L-mannopyranosyl)-D-glucopyranosyl]oxy}-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one.

M.S.:

CAS NO.:520-27-4

Physical Property: crystalline(pyridine); M.P.: 283ºC; solubility: insoluble in water and ethanol.

Plants source: rutaceous zanthoxylum nitidum (Roxb.) DC. Root [1];

rutaceous citrus medica L. var. sarcodatylis (Noot.) swingle fruit [2] C. Citrus lemon burm. Peel [3] Zanthoxylum avicennae (Lam.) DC. Bark [1]; sophora viciifolia hance leaf [4] capsella bursa-pastoris (L.) medic. Full plant [5] peel [6] rosmarinus officinalis L. full plant [7] scabiosa caucasica bieb.[8] scropularia nodosa lihnn.[9]

Indications: 

1,The same effect with vitamin P which has a better effect on lowering permeability of capillary than pyrocatechin hydrate, hesperidin, quercetin and rutin. 

2,The same effect with vitamin C2 which can increase resistance of capillary and reduce vitamin C elimination in adrenal gland.

3,Anti-inflammatory: intraperitoneal injection, with a detumescence effect on vola pedis edema which caused by Carragenan. ED50 at 100mg/kg.

4,Low toxicity, for the treatment of capillary frangibility. Dosage: oral administration of LD50 at 10g/kg, intraperitoneal injection of LD50 at 4g/kg.