Email:melody@hebeijimi.com
company name:Hebei Jimi Trading Co., Ltd.
company website:http://www.hebeijimi.com
About Us
Our company is the specialized Pharmaceutical chemicals, processing and sales enterprise.
our products enjoy good reputation both at home and abroad.Our trade partners are around the world, mainly in America,Europe,Australia,South East Asia ,Middle East and South Africa. In order to serve customers well, the company has established special technical department and after-sale service department. We will make careful reply if you get any question.
The company with all the employees will constantly purse excellent quality, perfect brand and our image, and adheres to our spirit of honesty, diligence, seeking truth and progress and insists on business philosophy of quality as life and service as soul. We will satisfy market demands by top products and better service, and will welcome market challenge forever.
Sincerely welcome domestic and external customers to negotiate and trade.
Quick Details
- ProName: AICAR
- CasNo: 2627-69-2 Molecular Formula: C9H14N4O5
- Appearance: white or off-white powder Application: chemical raw material and research use...
- DeliveryTime: 15 DAYS PackAge: Aluminum drum or foil bag
- Port: SHANGHAI ProductionCapacity: 10 Metric Ton/Month
- Purity: min 99% Storage: storage in norm temperature and agains...
- Transportation: by Air or Sea LimitNum: 1 Kilogram
- Moisture Content: NMT 0.3% Impurity: NMT 0.1%
- Uses
- AICAR (AICA-Riboside) strongly inhibits the transcription of PPARα and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).
China
