| 4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Basic information |
| Product Name: |
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole |
| Synonyms: |
4-chloro-7-nitro-benzofuraza;4-nitro-7-chlorobenzofurazan;nbd-c1;7-CHLORO-4-NITRO-2,1,3-BENZOXADIAZOL;7-CHLORO-4-NITROBENZO-2-OXA-1,3-DIAZOLE;7-CHLORO-4-NITROBENZOFURAZAN;AKOS BC-0686;4-CHLORO-7-NITRO-2,1,3-BENZOXADIAZOLE |
| CAS: |
10199-89-0 |
| MF: |
C6H2ClN3O3 |
| MW: |
199.55 |
| EINECS: |
233-496-4 |
| Product Categories: |
Miscellaneous;Amino Group Labeling Reagents for Fluorescence HPLC;Analytical Chemistry;Fluorescence Detection (HPLC Labeling Reagents);HPLC Labeling Reagents;Mercapto Group Labeling Reagents for Fluorescence HPLC;Pharmaceutical intermediate;Aromatics;Fluorescent Labels & Indicators;Heterocycles;Functional Group Reactive Labels for Immunoassays;Biochemicals and Reagents;Building Blocks;Chemical Synthesis;Derivatization agents;Fluorescent Probes;Functional Group Reactive Labels;Halogenated Heterocycles;Heterocyclic Building Blocks;Labels;Luminescent Compounds/Detection;Oxadiazoles;Particles and Stains |
| Mol File: |
10199-89-0.mol |
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| 4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Chemical Properties |
| Melting point |
97-99 °C(lit.) |
| density |
2.0589 (rough estimate) |
| refractive index |
1.5810 (estimate) |
| storage temp. |
2-8°C |
| solubility |
Soluble in methanol, dimethylsulfoxide, dimethylformamide and chloroform. |
| form |
Crystalline Powder |
| color |
Yellow to light brown |
| Water Solubility |
soluble |
| BRN |
614212 |
| CAS DataBase Reference |
10199-89-0(CAS DataBase Reference) |
| EPA Substance Registry System |
2,1,3-Benzoxadiazole, 4-chloro-7-nitro-(10199-89-0) |
| Hazard Codes |
Xn,Xi |
| Risk Statements |
22-36/38 |
| Safety Statements |
36/37/39 |
| RIDADR |
UN 2811 6.1/PG 3 |
| WGK Germany |
3 |
| RTECS |
DF8002400 |
| F |
10-21 |
| TSCA |
Yes |
| Provider |
Language |
| SigmaAldrich |
English |
| ACROS |
English |
| ALFA |
English |
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| 4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Usage And Synthesis |
| Chemical Properties |
yellow to light brown crystalline powder |
| Uses |
NBD chloride is nonfluorescent until it reacts with primary or secondary amines to produce a fluorescent product. NBD chloride has been extensively used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines. |
| Uses |
A fluorescent reagent |
| Definition |
ChEBI: A benzoxadiazole that is 2,1,3-benzoxadiazole which is substituted at position 4 by chlorine and at position 7 by a nitro group. |
| Purification Methods |
Wash the solid with H2O, and it recrystallises from aqueous EtOH (1:1) as pale yellow needles. It sublimes in a vacuum [Gosh & Whitehouse Biochem J 108 155 1968, UV, NMR: Bolton et al. J Chem Soc 1004 1966]. |
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| 4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Preparation Products And Raw materials |
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| 7-CHLORO-N,N-DIETHYL-4-NITRO-2,1,3-BENZOXADIAZOL-5-AMINE 2-(7-CHLORO-4-NITRO-BENZO[1,2,5]OXADIAZOL-5-YLAMINO)-ETHANOL 3-(7-CHLORO-4-NITRO-BENZO[1,2,5]OXADIAZOL-5-YLAMINO)-PROPAN-1-OL AKOS BB-7022 7-CHLORO-5-(4-METHYL-PIPERAZIN-1-YL)-4-NITRO-BENZO[1,2,5]OXADIAZOLE 7-CHLORO-5-MORPHOLIN-4-YL-4-NITRO-BENZO[1,2,5]OXADIAZOLE (7-CHLORO-4-NITRO-BENZO[1,2,5]OXADIAZOL-5-YL)-PYRIDIN-2-YL-AMINE 5-AMINO-7-CHLORO-4-NITROBENZOFURAZAN 4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole N-[4-(7-CHLORO-4-NITRO-BENZO[1,2,5]OXADIAZOL-5-YLAMINO)-PHENYL]-ACETAMIDE TIMTEC-BB SBB005650 (7-CHLORO-4-NITRO-BENZO[1,2,5]OXADIAZOL-5-YL)-DIMETHYL-AMINE 4-CHLORO-5,7-DINITROBENZOFURAZAN 5-AZEPAN-1-YL-7-CHLORO-4-NITRO-BENZO[1,2,5]OXADIAZOLE N-BENZYL-4-NITRO-2,1,3-BENZOXADIAZOL-5-AMINE 7-CHLORO-4-NITRO-5-PYRROLIDIN-1-YL-BENZO[1,2,5]OXADIAZOLE 7-CHLORO-4-NITRO-5-PIPERIDINO-2,1,3-BENZOXADIAZOLE 7-CHLORO-5-(4-METHYL-PIPERIDIN-1-YL)-4-NITRO-BENZO[1,2,5]OXADIAZOLE |
China
