CAS: | 1953-54-4 |
MF: | C8H7NO |
MW: | 133.15 |
EINECS: | 217-782-6 |
Product Categories: | Heterocycle-Indole series;Building Blocks;Indoles;C7 to C9;Chemical Synthesis;Heterocyclic Building Blocks;blocks;IndolesOxindoles;indole derivative;Indoles and derivatives;pharmacetical;Indole;Simple Indoles |
Mol File: | 1953-54-4.mol |
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5-Hydroxyindole Chemical Properties |
Melting point | 106-108 °C(lit.) |
Boiling point | 245.66°C (rough estimate) |
density | 1.1475 (rough estimate) |
refractive index | 1.5260 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
solubility | 38g/l |
form | Crystalline Needles or Powder |
pka | 9.98±0.40(Predicted) |
color | beige |
Sensitive | Light Sensitive |
BRN | 112349 |
CAS DataBase Reference | 1953-54-4(CAS DataBase Reference) |
NIST Chemistry Reference | Indol-5-ol(1953-54-4) |
5-Hydroxyindole Usage And Synthesis |
Chemical Properties | beige to brown crystalline needles or powder |
Uses | • ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6 |
Uses | 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptop han (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets. |
Uses | 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets. |
Definition | ChEBI: 5-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group. It has a role as a human metabolite. |
Synthesis Reference(s) | Journal of the American Chemical Society, 76, p. 5579, 1954 DOI: 10.1021/ja01651a001 The Journal of Organic Chemistry, 49, p. 4833, 1984 DOI: 10.1021/jo00199a017 |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms) | 1 - 10000 | >10000 |
Est. Time(days) | 5 | To be negotiated |
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Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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