Description: Fluorouracil (5-FU) is a pyrimidine analogue used as an antineoplastic agent to treat multiple solid tumors including colon, rectal, breast, gastric, pancreatic, ovarian, bladder and liver cancer.
Synonym: 5 Fluorouracil, 5 Fluorouracil biosyn, 5-Fluorouracil-biosyn, 5-FU, 5-FU Lederle, 5-FU medac, Fluoroplex, Efudex, Adrucil, Carac, Fluracil, Fluoroblastin, 5-Flouracyl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Melting Point: 282-286 °C (dec.) (lit.)
Boiling Point: 190-200°C/0.1mmHg
Shipping Condition: Shipped under ambient temperature. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Light Sensitive. Store in a light resistant container. Keep container tightly closed. Keep container in a cool, well ventilated area.
Shelf Life: >2 years if stored properly
HS Tariff Code: 2933990099
More Info: Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances from becoming incorporated into DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.
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