Description:
Chemical Structure and Properties:
Chemical Formula: C27H42O5
Molecular Weight: 446.62 g/mol
Chemical Name: 5α-Hydroxy Laxogenin
Other Names: 5a-Hydroxy Laxogenin, Laxosterone
Sources:
5-alpha-Hydroxy-Laxogenin is a plant-derived steroidal sapogenin. It is found in small amounts in the plant Smilax sieboldii, which belongs to the family Smilacaceae.
It can also be synthesized in the laboratory for use in dietary supplements.
Mechanism of Action
5-alpha-Hydroxy-Laxogenin is often categorized as a plant-based anabolic compound, although its exact mechanism of action is not fully understood. Here are some proposed mechanisms:
Protein Synthesis: It is believed to enhance protein synthesis, thereby promoting muscle growth and recovery. This is similar to the action of anabolic steroids but without the androgenic side effects.
Cortisol Regulation: It may help reduce cortisol levels, a stress hormone that can lead to muscle breakdown and fat gain.
Nitrogen Retention: Improved nitrogen retention can contribute to an anabolic environment in the body, supporting muscle growth.
Uses and Applications
Bodybuilding and Athletic Performance:
Muscle Growth: 5-alpha-Hydroxy-Laxogenin is popular among bodybuilders and athletes for its potential to enhance muscle growth and strength.
Recovery: It may aid in faster recovery from intense workouts by promoting protein synthesis and reducing muscle soreness.
Fat Loss: Some users report improved body composition, including fat loss, likely due to its potential effect on cortisol levels.
General Health and Wellness:
Anti-Inflammatory Properties: Preliminary research suggests that 5-alpha-Hydroxy-Laxogenin may have anti-inflammatory effects, which can be beneficial for joint health and overall well-being.
Adaptogen: It may act as an adaptogen, helping the body cope with physical and mental stress.
Dosage and Administration
Forms: 5-alpha-Hydroxy-Laxogenin is available in various forms, including capsules, tablets, and powders.
Dosage: Typical doses range from 50 mg to 200 mg per day, often divided into two doses. However, the optimal dosage can vary depending on individual goals and body weight.
Administration: It is usually taken with meals to enhance absorption.
Safety and Side Effects
Safety: 5-alpha-Hydroxy-Laxogenin is generally considered safe when used as directed. However, long-term safety data is limited, and it is advisable to consult a healthcare provider before starting supplementation, especially for individuals with pre-existing medical conditions or those taking other medications.
Side Effects: Reported side effects are minimal but may include mild gastrointestinal discomfort or headaches. As with any supplement, individual responses can vary.
Regulatory Status
Dietary Supplements: In many countries, including the United States, 5-alpha-Hydroxy-Laxogenin is available as a dietary supplement. However, it is not approved by regulatory agencies like the FDA for any specific medical use.
Athletic Competitions: Athletes should be cautious, as the status of 5-alpha-Hydroxy-Laxogenin in competitive sports can vary. It is advisable to check with relevant sports governing bodies regarding its legality.
Conclusion
5-alpha-Hydroxy-Laxogenin is a plant-derived compound that has gained popularity for its potential anabolic effects, particularly in the fields of bodybuilding and athletic performance. While it is generally considered safe and well-tolerated, more research is needed to fully understand its mechanisms and long-term effects. As always, it is important to consult with a healthcare provider before starting any new supplement regimen.
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Storage Condition: Dry, dark, and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).