| CAS: | 42348-86-7 |
| MF: | C9H7ClO |
| MW: | 166.6 |
| EINECS: | 610-016-5 |
| Product Categories: | Building Blocks;C9;Carbonyl Compounds;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Benzocycles;Indane/Indanone and Derivatives;Ketones;Indanone & Indene;42348-86-7 |
| Mol File: | 42348-86-7.mol |
 |
|
| 5-Chloro-1-indanone Chemical Properties |
| Melting point | 94-98 °C (lit.) |
| Boiling point | 124-125 °C (3 mmHg) |
| density | 1.1466 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| Fp | 124-125°C/3mm |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly) |
| form | Solid |
| color | Light Beige to Beige |
| Water Solubility | insoluble |
| BRN | 1448000 |
| InChIKey | MEDSHTHCZIOVPU-UHFFFAOYSA-N |
| CAS DataBase Reference | 42348-86-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Chloro-1-indanone(42348-86-7) |
| EPA Substance Registry System | 1H-Inden-1-one, 5-chloro-2,3-dihydro- (42348-86-7) |
| 5-Chloro-1-indanone Usage And Synthesis |
| Chemical Properties | White Crystal |
| Uses | 5-Chloro-1-indanone is the important intermediate of du pont company's new varieties of pesticides indoxacarb (popular name: indoxacarb), is also a kind of important medicine intermediate simultaneously.
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.
5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. |
| Uses | 5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines. |
| Preparation | 3-chlorobenzaldehyde as raw material first reacts with propionic acid to prepare 3-chloro-phenylpropionic acid, which is then subjected to Friedel-Crafts acylation reaction to prepare 5-chloro-1-indanone. Organic solvents of formic acid diethylamine participate in the first step, and the reaction temperature is 20-150℃. An organic solvent of methylene chloride and a catalyst of zinc chloride participate in the second step, and the reaction temperature is -10 to 80 ℃.
Synthetic method of 5-chloro-1-indanone |
| General Description | 5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types. |
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
Advantage
In stock
Japan
