Chinese name: 2-amino-4-chloro-pyridine
English name: 2-Amino-4-chloropyridine
CAS number: 19798-80-2
Molecular formula: C5H5ClN2
Molecular weight: 128.56
EINECS number: 629-610-0
Melting point: 126-127°C
Boiling point: 240.8±20.0°C(Predicted)
Density: 1.326±0.06g/cm3(Predicted)
Article storage KeChemicalbookepindarkplace Sealedindry RoomTemperature
Solubility: Soluble in dimethyl sulfoxide and methanol
Form: Liquid
Acidity coefficient (pKa) : 5.72±0.11(Predicted)
Color: Colorless to yellow to brown
Maximum wavelength (λmax) : 294nm(CHCl3)(lit.)
Sensitivity: Air & Moisture Sensitive
InChI: InChI = 1 s/C5H5ClN2 / c6-4-1-2-8-5 (7)/h1 3-4-3 h, (H2, 7, 8)
InChIKey: RQMWVVBHJMUJNZ-UHFFFAOYSA-N
SMILES: C1(N)=NC=CC(Cl)=C1
Description: 2-amino-4-chloro-pyridine is a white solid, which can be prepared from 2-pyridine carboxylic acid as a raw material, and then react with calcium hypochlorite to obtain 2-amino-4-chloro-pyridine.
Application: 2-amino-4-chlorochemicalbook-pyridine can be used to prepare 4-fluoro-2-aminopyridine, 4-fluoro-2-aminopyridine is an important intermediate in the preparation of tyrosine kinase inhibitors, P13K inhibitors and aldosterone synthase inhibitors, and has a wide range of application prospects.
China
