Description |
Lornoxicam (Trade name: “Xefo”) belongs to a non-steroidal anti-inflammatory drug. As a kind of oxicam class drug, it has analgesic, anti-inflammatory and antipyretic properties. It can be used for the treatment of various type of acute mild to moderate pain which results from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and rheumatic diseases. Lornoxicam is capable of potently inhibiting the prostaglandin biosynthesis process, making it have highly pronounced efficacy. The exact mechanism of Lornoxicam is not exactly understood. However, it is indicated that Lornoxicam can inhibit the prostaglandin and thromboxane synthesis by inhibiting both COX-1 and COX-2, leading to reduction of inflammation, pain, fever, and swelling. |
References |
https://www.drugbank.ca/drugs/DB06725
https://en.wikipedia.org/wiki/Lornoxicam |
Chemical Properties |
Crystalline Solid |
Uses |
keratolytic, antiacne, antineoplastic |
Uses |
ocular vasoconstrictor |
Uses |
For the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases. |
Uses |
Cyclooxygenase inhibitor; structurally similar to tenoxicam. Anti-inflammatory; analgesic |
Definition |
ChEBI: A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for th treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations. |