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Procarbazine hydrochloride

$ 1.00 /1KG

Min. Order1G
Purity98%
Cas No366-70-1
Supply Ability100KG
Update time2019-07-06

career henan chemical co

career henan chemical co

7YR

China

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Chemical Properties

Product Name	Procarbazine hydrochloride
CAS No	366-70-1
EC-No
Min. Order	1G
Purity	98%
Supply Ability	100KG
Release date	2019/07/06

AD68

Procarbazine hydrochloride Basic information

Product Name:	Procarbazine hydrochloride
Synonyms:	n-(1-methylethyl)-4-((2-methylhydrazino)methyl)benzamide hydrochloride;PROCARBAZINE HCL;PROCARBAZINE HYDROCHLORIDE;1-(p-isopropylcarbamoylbenzyl)-2-methylhydrazinehydrochloride;1-methyl-2-(p-isopropylcarbamoylbenzyl)hydrazinehydrochloride;1-methyl-2-p-(isopropylcarbamyol)benzohydrazinehydrochloride;2-(p-(isopropylcarbamoyl)benzyl)-1-methylhydrazinehydrochloride;chlorhydratede1-methyl2p(isopropylcarbamoyl)benzyl-hydrazine
CAS:	366-70-1
MF:	C12H20ClN3O
MW:	257.76
EINECS:	206-678-6
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;API;Matulane
Mol File:	366-70-1.mol

Procarbazine hydrochloride Chemical Properties

Melting point	223°C
storage temp.	-20°C Freezer
solubility	DMSO: ≥18mg/mL
color	white to tan
Water Solubility	>=10 g/100 mL at 21.5 ºC
Merck	14,7758
CAS DataBase Reference	366-70-1(CAS DataBase Reference)
EPA Substance Registry System	Benzamide, N-(1-methylethyl)-4-[(2-methylhydrazino) methyl]-, monohydrochloride(366-70-1)

Safety Information

Hazard Codes	T
Risk Statements	45-61-22-68
Safety Statements	53-36/37-45
RTECS	XS4725000
Toxicity	LD50 orally in rats: 785 ±34 mg/kg (Goldenthal)

Procarbazine hydrochloride Usage And Synthesis

Chemical Properties	Crystalline Solid
Uses	Antineoplastic;DNA replication inhibitor
Definition	ChEBI: A hydrochloride obtained by combining procarbazine with one equivalent of hydrochloric acid. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaki g of DNA strands.
General Description	White to pale yellow crystalline powder with a slight odor. Acid to litmus.
Air & Water Reactions	In the presence of moisture or in aqueous solution undergoes oxidation by atmospheric oxygen. Water soluble.
Reactivity Profile	Procarbazine hydrochloride is very sensitive to light. Stability is highest in aqueous acid and decreases with increasing pH. Degrades rapidly in alcoholic media and more slowly in aqueous media .
Fire Hazard	Flash point data for Procarbazine hydrochloride are not available; however, Procarbazine hydrochloride is probably combustible.

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