Mosapride citrate

$ 1.00 /1KG

Min. Order1G
Purity98%
Cas No112885-42-4
Supply Ability100KG
Update time2019-07-06

career henan chemical co

7YR

China

Chemical Properties

Product Name	Mosapride citrate
CAS No	112885-42-4
EC-No
Min. Order	1G
Purity	98%
Supply Ability	100KG
Release date	2019/07/06

AD68

Mosapride citrate Basic information

Product Name:	Mosapride citrate
Synonyms:	4-AMINO-5-CHLORO-2-ETHOXY-N-[[4-(4-FLUOROBENZYL)-2-MORPHOLINYL]METHYL]BENZAMIDE CITRATE DIHYDRATE;4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-benzamide 2-hydroxy-1,2,3-propanetricarboxylate;Gasmotin;4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;4-azanyl-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamidecitrate;Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, 2-hydroxy-1,2,3-propanetricarboxylate;4-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)morpholin-2-yl)methyl)benzamide 2-hydroxypropane-1,2,3-tricarboxylate
CAS:	112885-42-4
MF:	C27H37ClFN3O12
MW:	650.05
EINECS:	1806241-263-5
Product Categories:	Gastroprokinetic Agent;APIS;API;TAK-370, AS-4370, Gasmotin;Inhibitors
Mol File:	112885-42-4.mol

Mosapride citrate Chemical Properties

Melting point	143-145°
storage temp.	Desiccate at RT
CAS DataBase Reference	112885-42-4(CAS DataBase Reference)

Safety Information

Toxicity

LD50 in male, female mice, rats (mg/kg): >3000, >3000, >3000, 1905 orally; >1000, 914, >1000, >1000 i.p.; all species >1000 s.c.; in male, female dogs (mg/kg): both >400 orally (Yatera)

MSDS Information

Mosapride citrate Usage And Synthesis

Uses	Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist which accelerates gastric emptying and is used for the treatment of acid reflux, irritable bowel syndrome and functional dyspepsia
Uses	A selective SR-4 activator and a SR-3 inhibitor
Biological Activity	5-HT 4 receptor agonist and 5-HT 3 receptor antagonist. Displays no activity at D 2 , α 1 , α 2 , 5-HT 1 and 5-HT 2 receptors. Gastroprokinetic agent; increases gastric emptying in rats and stimulates gastric motor actvity in conscious dogs.

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