Mosapride citrate NEW

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Min. Order1KG
Purity99.9%
Cas No112885-42-4
Supply Ability500kg/month
Update time2026-06-12

Wuhan Fortuna Chemical Co., Ltd

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Chemical Properties

Product Name	Mosapride citrate
CAS No	112885-42-4
EC-No	601-211-6
Min. Order	1KG
Purity	99.9%
Supply Ability	500kg/month
Release date	2026/06/12

Mosapride citrate is the citrate salt of mosapride, a selective 5-HT₄ (serotonin) receptor agonist used clinically as a gastroprokinetic agent to enhance gastric motility. Chemically, it is a benzamide derivative.

Pharmaceutical vs. Chemical Grade

Pharmaceutical Grade: Formulated into tablets for treating functional dyspepsia, gastroesophageal reflux disease (GERD), and gastroparesis.
Chemical/Research Grade: A high-purity (typically ≥98%), solid powder with a defined chemical structure (CAS: 112885-42-4), sold for non-therapeutic laboratory use.

Primary Uses in Chemical and Research Grades

As a research chemical, it serves as a selective pharmacological tool:

Biochemical & Pharmacological Research:

Selective 5-HT₄ Receptor Agonist: Used in in vitro assays (e.g., cell lines expressing 5-HT₄ receptors) and in vivo animal models to study the specific role of 5-HT₄ receptor signaling in gastrointestinal motility, visceral sensitivity, and neurotransmitter release.
Mechanism Studies: A tool to investigate downstream pathways of 5-HT₄ activation and compare efficacy/selectivity against other prokinetic agents (e.g., metoclopramide).

Analytical Reference Standard:

Primary Standard: Used in HPLC, LC-MS/MS, and other analytical methods for quantitative analysis, quality control, and method validation during pharmaceutical manufacturing of mosapride products.
Bioanalytical Applications: Essential for developing assays to measure mosapride concentration in biological samples (plasma, tissue) for pharmacokinetic and metabolism studies.

Metabolic and Toxicology Studies:

Used to identify and characterize its metabolites (primarily via CYP3A4 metabolism) and to assess preclinical safety profiles in controlled research settings.

Key Distinction for Handling

Not for Human Use: Strictly for laboratory research.
Handling & Storage: Store in a cool, dry place. Handle using standard laboratory safety practices; avoid inhalation or direct contact.
Solubility: Soluble in DMSO and methanol, slightly soluble in water, which informs its preparation for in vitro studies.

Summary

Aspect	Description
Identity	Citrate salt of a selective 5-HT₄ receptor agonist (benzamide class).
Chemical Grade	High-purity reference material for non-therapeutic research.
Primary Research Uses	1. Pharmacological Tool: For selective 5-HT₄ receptor studies in GI physiology. 2. Analytical Standard: For quantification and method validation. 3. Metabolism Studies: To investigate its metabolic fate.

In essence, chemical-grade mosapride citrate is a selective receptor agonist used as a precise tool for gastrointestinal pharmacology research, analytical chemistry, and drug metabolism studies.