Basic information Description Chemical Properties Indications Uses References Safety Related Supplier

ChemicalBook Product Catalog API Anesthetic Agents Local anesthetics Dyclonine hydrochloride

1/1

Dyclonine hydrochloride

$ 1.00 /1KG

Min. Order1G
Purity98%
Cas No536-43-6
Supply Ability100KG
Update time2019-07-06

career henan chemical co

career henan chemical co

7YR

China

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Chemical Properties

Product Name	Dyclonine hydrochloride
CAS No	536-43-6
EC-No
Min. Order	1G
Purity	98%
Supply Ability	100KG
Release date	2019/07/06

AD68

Dyclonine hydrochloride Basic information

Description References

Product Name:	Dyclonine hydrochloride
Synonyms:	DYCLONINE HCL;DYCLONINE HYDROCHLORIDE;LABOTEST-BB LT00771942;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HCL;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HYDROCHLORIDE;1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanonhydrochloride;4’-butoxy-3-piperidinopropiophenonehydrochloride;4’-butoxy-3-piperidino-propiophenonhydrochloride
CAS:	536-43-6
MF:	C18H28ClNO2
MW:	325.87
EINECS:	208-633-6
Product Categories:	Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;API;DYCLONE;research chemical
Mol File:	536-43-6.mol

Dyclonine hydrochloride Chemical Properties

Melting point	175-176°C
storage temp.	-20°C Freezer
Water Solubility	Partly soluble in water. Soluble in chloroform, ethanol, acetone and methanol.
Merck	14,3473
InChIKey	KNZADIMHVBBPOA-UHFFFAOYSA-N
CAS DataBase Reference	536-43-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	22-37/38-41
Safety Statements	26-36
RIDADR	3249
WGK Germany	3
RTECS	UG8750000
HazardClass	6.1(b)
PackingGroup	III

Dyclonine hydrochloride Usage And Synthesis

Description	Dyclonine hydrochloride is the hydrochloride salt of Dyclonine. Dyclonine belongs to a kind of oral anaesthetic. It is contained in the “Sucrets” as well as some kinds of Cepacol sore throat spray as an active ingredient. Dyclonine takes effect through reversibly binding to the activated sodium channels located on the neuronal membrane. This decreases the permeability of sodium across the neuronal membrane, further increasing the threshold for excitation. Overall, Dyclonine stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and further suppressing the subsequent conduction. This causes a transient and reversible anaesthetic effect in a local area of the body.
References	https://en.wikipedia.org/wiki/Dyclonine https://pubchem.ncbi.nlm.nih.gov/compound/Dyclonine_hydrochloride#section=Top
Chemical Properties	White Crystalline Solid
Uses	anesthetic (topical)
Uses	Used as a local anesthetic
Definition	ChEBI: The hydrochloride salt of dyclonine.

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