Clindamycin phosphate

$ 1.00 /1KG

career henan chemical co

VIP8Y

China

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Chemical Properties

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Clindamycin phosphate Basic information

Product Name:	Clindamycin phosphate
Synonyms:	(2s-trans)-;2-(dihydrogenphosphate;7(s)-chloro-7-deoxylincomycin2-phosphate;cleocinphosphate;dalacinp;l-threo-alpha-d-galacto-octapyranoside,methyl7-chloro-6,7,8-trideoxy-6-(((1-m;u28508;methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-l-2-pyrrolidinecarboxamido)-1-thio-l-threo-alpha-d-galacto-octopyranoside 2-(dihydrogen phosphate)
CAS:	24729-96-2
MF:	C18H34ClN2O8PS
MW:	504.97
EINECS:	246-433-0
Product Categories:	Antibiotics for Research and Experimental Use;Biochemistry;Others (Antibiotics for Research and Experimental Use);API's;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	24729-96-2.mol

Clindamycin phosphate Chemical Properties

Melting point	114 °C
Boiling point	159°C
refractive index	122 ° (C=1, H2O)
storage temp.	2-8°C
solubility	DMSO: soluble224mg/mL at 25°C
form	solid
Water Solubility	Freely soluble in water
Merck	14,2356
Stability:	Stable, but store cool. Incompatible with strong oxidizing agents, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, B group sodium vitamins.

Safety Information

Clindamycin phosphate Usage And Synthesis

Chemical Properties	solid
Uses	antibacterial
Uses	Clindamycin (C580000) impurity in bulk drug.
Uses	A highly water soluble Clindamycin prodrug.
Uses	Clindamycin 2-phosphate is a a salt of clincamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis.
Uses	Clindamycin 2-phosphate is a salt of clindamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis.

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