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ChemicalBook Product Catalog Food Additives Colorant Nonivamide

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Nonivamide

$ 300.00 /1KG

Min. Order10G
Purity99%
Cas No2444-46-4
Supply Abilitycustomise
Update time2019-07-06

career henan chemical co

career henan chemical co

VIP8Y

China

China

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Chemical Properties

Product Name	Nonivamide
CAS No	2444-46-4
EC-No
Min. Order	10G
Purity	99%
Supply Ability	customise
Release date	2019/07/06

Product Number：WM0172

Product Information：

Product Name:	Nonivamide
Synonyms:	Nonivamide(Synthetic Capsaicin);N-((Hydroxy-3-methoxyphenyl)methyl)4-nonanamide;N-Nonanoyl vanillylamide;Nonanamide, N-((4-hydroxy-3-methoxyphenyl)meth;n-((4-hydroxy-3-methoxyphenyl)methyl)-nonanamid;n-[(4-hydroxy-3-methoxyphenyl)methyl]-nonanamid;Nonanoylvanilylamide;nonylicacidvanillylamide(nonivamide)
CAS:	2444-46-4
MF:	C17H27NO3
MW:	293.4
EINECS:	219-484-1
Product Categories:	Inhibitors;API;INORGANIC & ORGANIC CHEMICALS;Anilines, Aromatic Amines and Nitro Compounds;Plant extract;Herb extract
Mol File:	2444-46-4.mol

Nonivamide Chemical Properties

Melting point	54°C
density	1,1 g/cm³
FEMA	2787 \| NONANOYL 4-HYDROXY-3-METHOXYBENZYLAMIDE
Fp	190°C
storage temp.	2-8°C
solubility	methanol: 100 mg/mL, clear to slightly hazy
form	powder
color	white to off-white
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	2444-46-4(CAS DataBase Reference)
EPA Substance Registry System	Nonanamide, N-[(4-hydroxy-3-methoxyphenyl) methyl]-(2444-46-4)

Safety Information

Hazard Codes	T,Xi
Risk Statements	25-36/37/38-43
Safety Statements	26-45-37/39-36/37
RIDADR	UN 3462 6.1/PG 2
WGK Germany	3
RTECS	RA5998000
F	19
HazardClass	6.1
PackingGroup	II

MSDS Information

Provider	Language
SigmaAldrich	English

Nonivamide Usage And Synthesis

Description	Nonivamide is also called pelargonic acid vanillylamide or PAVA. It is a capsaicinoid. Nonivamide, isolated from peppers, is a naturally occurring analog of capsaicin (sc-3577). Similar to capsaicin, nonivamide can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A. Nonivamide is with lower TRPV1 binding affinity, thus, a reduced pungency (9 200 000 scoville heat units) compared to capsaicin (16 000 000 scoville heat units). Nonivamide is used in the food production to add a hot sensation to flavoring agents and spice mixtures. It is also used in the sweets and confectionary industries to add hot sensation into products. In pharmaceutical industries, nonivamide is used as a cheaper alternative for capsaicin. Warming or heating ointment of nonivamide is used for temporary relief of pain from conditions such as rheumatism, arthritis, lumbao, muscular aches, sprains and strains, sporting injuries and other conditions where local warmth is beneficial. Finalgon is one of the common product utilizing nonivamide for this purpose. Nonivamide is also used as an incapacitant spray, affecting the assailed person’s eyes, causing intense pain and swelling.
References	[1] https://www.scbt.com/scbt/product/nonivamide-2444-46-4 [2] https://pubchem.ncbi.nlm.nih.gov/compound/N-Vanillylnonanamide#section=Clinical-Trials [3] https://cot.food.gov.uk/sites/default/files/cot/cotsection.pdf
Chemical Properties	solid
Uses	analgesic (topical), depletes Substance P
Uses	N-Vanillylnonanamide is a synthetic analogue of Capsaicin (175680) with similar bioactivity.
Definition	ChEBI: A capsaicinoid that is the carboxamide resulting from the formal condensation of the amino group of 4-hydroxy-3-methoxybenzylamine with the carboxy group of nonanoic acid. It is the active ingredient in many pepper sprays.

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