Venlafaxine hydrochloride

$ 100.00 /25KG

Min. Order1KG
Purity98%
Cas No99300-78-4
Supply Ability1T
Update time2019-07-06

career henan chemical co

7YR

China

Chemical Properties

Product Name	Venlafaxine hydrochloride
CAS No	99300-78-4
EC-No	200-659-6
Min. Order	1KG
Purity	98%
Supply Ability	1T
Release date	2019/07/06

CR069

Venlafaxine hydrochloride Basic information

Product Name:	Venlafaxine hydrochloride
Synonyms:	Venlafaxine hydrochloride solution;Effexor hydrochloride;Wy 45030 hydrochloride;EFFEXOR;D,L-VENLAFAXINE;D,L-VENLAFAXINE, HYDROCHLORIDE;1-[2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL, HCL;1-[2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL HYDROCHLORIDE
CAS:	99300-78-4
MF:	C17H28ClNO2
MW:	313.86
EINECS:	200-659-6
Product Categories:	Active Pharmaceutical Ingredients;Medicine intermediate;Antidepressant;APIs;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Serotonin receptor
Mol File:	99300-78-4.mol

Venlafaxine hydrochloride Chemical Properties

Melting point	207-209°C
Fp	9℃
storage temp.	Store at RT
solubility	H2O: >10mg/mL
color	white
Merck	14,9946
InChIKey	QYRYFNHXARDNFZ-UHFFFAOYSA-N
CAS DataBase Reference	99300-78-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,T,F
Risk Statements	36/37/38-36-39/23/24/25-23/24/25-11
Safety Statements	26-37/39-45-36/37-16-7
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
RTECS	GV8872760
Hazardous Substances Data	99300-78-4(Hazardous Substances Data)

MSDS Information

Venlafaxine hydrochloride Usage And Synthesis

Chemical Properties	White Crystalline Powder
Uses	A selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant
Uses	An inhibitor of ST and SLC6A2.
Uses	Venlaxafine is an inhibitor of reuptake of both serotonin (IC50 = 0.21 μM) and norepinephrine (IC50 = 0.64 μM). It is effective in vitro and in vivo and against human as well as rat receptors. As an antidepressant, it is properly placed in the serotonin-norepinephrine reuptake inhibitor class.[Cayman Chemical]
Biological Activity	Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (K i values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats.

Venlafaxine hydrochloride Preparation Products And Raw materials

Raw materials

Sodium hydroxide-->Hydrochloric acid-->Methanol-->Ammonia-->Hexane-->Formaldehyde-->Isopropanol-->Formic acid-->Nickel-->Cyclohexanone-->Tetrabutylammonium bromide-->4-Methoxybenzyl cyanide

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