Ethisterone
Product Name: Ethisterone
Synonyms: 4,17ALPHA-PREGNEN-17BETA-OL-20-YN-3-ONE;4,17a-pregnen-17b-ol-20-yn-3-one;
4,17A-PREGNEN-17B-OL-20-YNE;4-ANDROSTEN-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE;(8R,9S,10R,13S,14S,17R)-17-ETHYNYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,
14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE;ANHYDROHYDROXYPROGESTERONE;ANHYDROXYPROGESTERONE;17BETA-HYDROXY-4,
17ALPHA-PREGNEN-20-YN-3-ONE
CAS: 434-03-7
MF: C21H28O2
MW: 312.45
EINECS: 207-096-5
Packaging: 1kg/tin
Appearance: White or kind of white crystalline powder
Standard: enterprise standard
Grade: medical grade
Assay: 99%
Uses Synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone
Water Solubility: soluble in chloroform, DMSO (0.05 mg/ml), acetone (slightly ), ethanol (<1 mg/ml at 25°C),
and water (<1 mg/ml at 25°C).
storage temp. -20°C Freezer
Density:1.1±0.1 g/cm3
Melting point: 266-273ºC
Boiling point: 446.4±45.0 °C at 760 mmHg
flash point: 190.2±21.3 °C
Description:
A 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an
ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol.
Similar to progesterone,it's suitable for the treatment of sub camp bleeding or menorrhagia,
can also be used to prevent threatened abortion and habitual abortion.
Dosage:
① The treatment of dysfunctional uterine bleeding: Take 12.5mg every 8 hours, (in case of
emergency medicine 1 time every 3 hours, until the bleeding decreased obviously changed
after 8 hours 1 time), and then gradually reduced, until the maintenance dose of 2.5mg 1 time
daily, and even last 20 days; Also can be in the bleeding stops, daily add oral ethinyl estradiol
0.05mg or diethylstilbestrol 1mg, total 20 days.
② Infertility: Oral Ethisterone 2.5mg and ethinylestradiol 0.05mg, 1 time a day, and even last 20 days,
total of 3 cycles.
③ Dysmenorrhea, endometriosis: Begin 5-7 days after menstruation, orally 1 times daily 2.5mg, and
even last 20 days.
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