Furosemide Pharmaceutical Raw Materials Diuretic Drug CAS 54-31-9 API White Powder
Quick detail
| Product Name: |
Furosemide |
| Synonyms: |
LABOTEST-BB LT00244801; FUROSEMID; FUROSEMIDE; FRUSEMIDE; 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid; 4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID; 5-(AMINOSULPHONYL)-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID; 5-[AMINOSULFONYL]-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID |
| CAS: |
54-31-9 |
| MF: |
C12H11ClN2O5S |
| MW: |
330.74 |
| EINECS: |
200-203-6 |
| Product Categories: |
Organics;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Ion transporter and other ion channel; GABA;Aromatics;Heterocycles;Sulfur & Selenium Compounds;API;LASIX;Other APIs |
| Melting point |
220 °C (dec.)(lit.) |
| density |
1.606 |
| Fp |
11 °C |
| storage temp. |
2-8°C |
| Merck |
4309 |
| Stability: |
Stable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents. |
Furosemide Description
- Furosemide is a loop diuretic (water pill) that prevents your body from absorbing too much salt. This allows the salt to instead be passed in your urine.
- Furosemide is used to treat fluid retention (edema) in people withcongestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome.
- Furosemide is also used to treat high blood pressure(hypertension).
Uses of Furosemide
| Usage |
diuretic, antihypertensive |
| Usage |
Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic. |
| Usage |
This compound belongs to the aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring. |
| Uses |
The diuretic effect of this product is a strong and short,it is a potent diuretic for the treatment of edema caused by heart, liver, kidney and other diseases, in particular, the base cases which other diuretics are invalid to;it can be used to treat acute pulmonary edema, brain edema , acute renal failure and high blood pressure and other diseases; in combination with fluid infusion, the product can promote poison excretion. Rat oral LD50 is 2600-2820mg/kg.
|
Furosemide Application
It Mainly inhibits Na + and Cl-reabsorption in medullary and cortex of the medullary loop ascending branch crude segment ,
it can promote the excretion of sodium, chloride and potassium and affect the formation of renal medullary high osmotic pressure,
it can interfer the process of concentration and dilution of urine, and it can increase urine output.
This product can inhibit the activity of prostaglandin decomposition enzyme ,make the content of prostaglandin E2 increase,it has effect on expansion of blood vessels,
it also plays a role in the proximal tubule, glomerular filtration,
it can increase renal blood flow,and adjust renal blood flow distribution,and reduce blood flow so that the cortex surface blood flow increases,it promotes diuresis, its effect is fast and strong, it is used for other diuretics invalid cases.
Advantages:
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