1. Product information
| Product Name: | 4-Nitrophenyl chloroformate |
| CAS: | 7693-46-1 |
| MF: | C7H4ClNO4 |
| MW: | 201.56 |
| EINECS: | 231-706-9 |
| Mol File: | 7693-46-1.mol |
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| 4-Nitrophenyl chloroformate Chemical Properties |
| Melting point | 77-79 °C(lit.) |
| Boiling point | 159-162 °C19 mm Hg(lit.) |
| density | 1.5719 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| Fp | >110°C |
| storage temp. | 2-8°C |
| solubility | Soluble in acetone, chloroform, acetone, toluene and benzene. |
| form | isopropanol suspension |
| color | White to yellow-beige |
| Water Solubility | decomposes |
| Sensitive | Lachrymatory |
| BRN | 518127 |
| Stability: | Stable. Incompatible with strong bases, acids. Combustible. |
| 4-Nitrophenyl chloroformate Usage And Synthesis |
| Chemical Properties | Cream solid |
| Uses | 4-Nitrophenyl Chloroformate is an ester of chloroformic acid used in the immobilization of enzymes and other biomolecules. |
| Uses | 4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane. |
| Uses | 4-Nitrophenyl chloroformate can be used:
As a reagent for the activation of amines, alcohols and thiols. In the synthesis of 4-substituted phenyl derivatives of 1,2,4-triazolidindiones (urazoles). In the solid-phase synthesis of 3-aryl-2,4-quinazolinedione derivatives with potent anti-cancer property. In the preparation of poly(oxyethylene) modified dextrans. To synthesize a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA.
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2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
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