Use and synthesis method of 2-morpholineethanesulphonic acid Bioactive MES (2-morpholineethanesulphonic acid) is a kind of amphoteric ion buffer, which is effective in the range of pH 5.5-7.7. As a kind of Good's buffer, MES is widely used in plant culture medium, reagent solution and physiological experiment to adjust pH value. Chemical properties: light yellow paste. Flash point 149 ℃, flow point 60 ℃. 25 ℃ water solubility 1%. It has high detergency, excellent calcium soap dispersion and hard water resistance. Good biodegradability. Use This product is used as calcium soap dispersant in soap and soap. It can replace sodium tripolyphosphate as a low-phosphorus or non-phosphorus detergent. It can also be used as an active substance in liquid washing. It is used as a medium-foam mineral flotation agent in industry. In leather degreasing, dyes, pigments and pesticides are used as dispersants and wetting agents. Used as deinking agent in the printing industry. Use It can be used as a biological buffer for facial cleanser, shampoo foam bath, tableware detergent, hand sanitizer raw materials, etc. It can be used in biochemical diagnostic kits, DNA/RNA extraction kits and PCR diagnostic kits. The chemical name of the manufacturer's chemicalbook surfactant MES is sodium fatty acid methyl ester sulfonate. Common products include sodium stearate methyl ester sulfonate, sodium laurate methyl ester sulfonate, sodium cinnamate methyl ester sulfonate, and sodium palmitate methyl ester sulfonate. The preparation method of sodium methyl stearate sulfonate is introduced as an example. The preparation process of this product includes three steps: preparation of methyl stearate, sulfonation and neutralization of methyl stearate. Put lard into the reactor and add methanol, the molar ratio of which is 1 ∶ 2, and add sulfuric acid with a total feed of 0.3% as catalyst after heating and dissolving under stirring. After heating and refluxing for 6-7h, the transesterification reaction is completed. Move the material to the distillation tower to evaporate excess methanol, and then decompress to evaporate glycerin. Methyl stearate is prepared at the bottom of the boiler, and then methyl stearate is sent to the sulfonation kettle. Sulphur trioxide is used as sulfonating agent for sulfonation. The molar ratio of sulfur trioxide to methyl stearate is (1.2 ～ 1.25) ∶ 1. Dilute sulfur trioxide to about 6% to ensure that sulfur trioxide is fully absorbed. The reaction temperature is controlled at 70~90 ℃. After 4~6 hours of reaction, 12% sodium hypochlorite was used for bleaching. Finally, neutralize with sodium hydroxide aqueous solution to pH 8~8.5.
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