Ethyl 4-Methyl-2-(Methylthio)pyrimidine-5-carboxylate CAS 7234-25-5 | Leading Supplier of Multifunctional Pyrimidine Derivative Intermediates
[Core Keywords]: Ethyl 4-Methyl-2-(Methylthio)pyrimidine-5-carboxylate Supplier, CAS 7234-25-5, Pyrimidine Pharmaceutical Intermediates, Agrochemical Building Blocks
Product Basic Information
Chemical Name: Ethyl 4-Methyl-2-(Methylthio)pyrimidine-5-carboxylate
CAS Number: 7234-25-5 (Enhanced Title-Level Keyword)
Molecular Formula: C10H12N2O2S
Appearance: White to Light Yellow Crystalline Powder
Purity: ≥98.5% (HPLC, Pharmaceutical Intermediate Grade)
Key Physical and Chemical Properties (Structured Data Optimization)
| Property | Parameter Value |
|---|
| Molecular Weight | 224.28 g/mol |
| Melting Point | 102-105°C (Dynamic DSC Measurement) |
| Boiling Point (0.2 mmHg) | 185-190°C (Decomposition) |
| Density (25°C) | 1.24 g/cm³ |
| Solubility | Soluble in Acetone, DCM; Slightly Soluble in Ethanol; Insoluble in Water |
| Storage Conditions | Store in a cool, dry place away from light, 2-8°C, sealed |
| Hygroscopicity | ≤0.5% (25°C/60% RH) |
Upstream and Downstream Industry Chain Integration
Upstream Raw Materials and Core Intermediates:
Core Intermediates: 4-Methylpyrimidine-2-thiol, Ethyl Chloroformate
Process Optimization: Thioetherization-Esterification Coupling Technology (Overall Yield >85%, Impurities <0.3%)
Downstream Applications:
Anticancer Drugs: Precursor for Thymidylate Synthase Inhibitors
Agrochemical Fungicides: Synthesis of Methoxyacrylate Compounds
Optoelectronic Materials: Organic Semiconductor Dopant Modifier Monomers
CRO/CDMO: Kinase Inhibitor High-Throughput Screening Library Construction
Industry Solutions and Technical Advantages
Application Areas and Typical Scenarios:
| Application Area | Typical Scenario | Technical Advantages |
|---|
| Anticancer Drugs | Structural Modification of 5-Fluorouracil Derivatives | Ester Hydrolysis Selectivity >95% (LC-MS Verified) |
| Agrochemical Formulations | Development of Novel HPPD Inhibitor Molecular Skeletons | Light Resistance (Stability >90% under UV 300nm) |
| OLED Materials | Synthesis of Hole Transport Layer Crosslinking Agents | Purity ≥99.9% (Gradient Sublimation Process) |
| Molecular Probes | Targeted Protein Kinase Active Site Labels | Thioether Bond Directed Oxidation Yield >97% |
SEO Keyword Matrix and Core Word Layout:
Core Words: "Ethyl 4-Methyl-2-(Methylthio)pyrimidine-5-carboxylate Price", "CAS 7234-25-5 Technical Parameters", "High-Activity Pyrimidine Derivative Supplier"
Long-Tail Keyword Combinations: "Custom Production of Anticancer Drug Intermediates", "Raw Material Supplier for Methoxyacrylate Fungicides", "Pharmaceutical Grade 7234-25-5 Manufacturer"
Quality System and Service Commitments:
cGMP Compliant Production: Complies with ICH Q7 Active Pharmaceutical Ingredient (API) Starting Material Standards
Customized Services: Supports Orders from Gram to Hundred-Kilogram Levels (MOQ 50g)
Analysis Reports: Provides Full Documentation Including HPLC, 1H NMR, and Elemental Analysis
Global Logistics: UN 3077 Certified Packaging (Moisture-Proof Aluminum Foil Bags + Desiccant)
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