| CAS: | 1822-51-1 |
| MF: | C6H6ClN.ClH |
| MW: | 164.03 |
| EINECS: | 217-350-7 |
| Product Categories: | Pyridinium Compounds;blocks;Pyridines;Halides;Heterocycles;Pyridines, Pyrimidines, Purines and Pteredines;Pyridines derivates;Heterocyclic Compounds |
| Mol File: | 1822-51-1.mol |
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| 4-(Chloromethyl)pyridine hydrochloride Chemical Properties |
| Melting point | 166-173 °C(lit.) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | soluble in DMSO, Methanol |
| form | Fine Crystalline Powder |
| color | Yellow to orange |
| Water Solubility | 750 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| BRN | 3689154 |
| CAS DataBase Reference | 1822-51-1(CAS DataBase Reference) |
| 4-(Chloromethyl)pyridine hydrochloride Usage And Synthesis |
| Chemical Properties | YELLOW TO ORANGE FINE CRYSTALLINE POWDER |
| Uses | It finds its application as a reagent for protection of carboxyl termini of peptides as 4-picolyl esters, providing a polar 'handle' which aids in separation and purification of the peptide. The group can be introduced in the presence of a base, e.g. tetramethylguanidine, is stable to acid-catalyzed removal of Cbz protecting group and can be removed by base, Na in liquid ammonia or catalytic hydrogenolysis. It is also applied in conjunction with Amberlyst?15 resin in peptide synthesis. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals. |
| Purification Methods | Purify it by recrystallisation from EtOH or EtOH/dry Et2O. It melts between 171o and 175o, and the clear melt resolidifies on further heating at 190o and turns red to black at 280o but does not melt again. The picrate-hydrochloride (prepared in EtOH) has m 146-147o. The free base is an oil. [Mosher & Tessieri J Am Chem Soc 73 4925 1951, Beilstein 20 III/IV 2752.] |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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