1. Materials information
Names
| Name | 4-Chlorocinnamic acid |
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| Synonym | More Synonyms |
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3-(4-Chlorophenyl)acrylic acid Biological Activity
| Description | 4-Chlorocinnamic acid has inhibitory effects on tyrosinase. 4-Chlorocinnamic acid has antibacterial activity. 4-Chlorocinnamic acid also inhibits Colletotrichum gloeosporioides growth[1][2][3]. |
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| Related Catalog | Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase Signaling Pathways >> Anti-infection >> Bacterial |
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| References | [1]. Cui Y, et al. Inhibition kinetics and molecular simulation of p-substituted cinnamic acid derivatives on tyrosinase. Int J Biol Macromol. 2017 Feb;95:1289-1297. [2]. Silva RHN, et al. Antimicrobial Activity of 4-Chlorocinnamic Acid Derivatives. Biomed Res Int. 2019 Apr 23;2019:3941242. [3]. Kátia Aparecida de Siqueira, et al. Isolation of 4-chlorocinnamic acid from Streptomyces griseocarneus R132, and its inhibition activity against sweet pepper postharvest anthracnose. Biocontrol Science and Technology. Volume 32, 2022-Issue 6 |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 325.3±17.0 °C at 760 mmHg |
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| Melting Point | 248-250 °C(lit.) |
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| Molecular Formula | C9H7ClO2 |
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| Molecular Weight | 182.60 |
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| Flash Point | 150.5±20.9 °C |
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| Exact Mass | 182.013458 |
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| PSA | 37.30000 |
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| LogP | 2.94 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.628 |
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| Storage condition | Room temperature. |
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MSDS
3-(4-Chlorophenyl)acrylic acid MSDS(Chinese) |
Toxicological Information
CHEMICAL IDENTIFICATIONCHEMICAL NAME : Cinnamic acid, p-chloro-
CAS REGISTRY NUMBER : 1615-02-7
MOLECULAR FORMULA : C9-H7-Cl-O2
HEALTH HAZARD DATAACUTE TOXICITY DATASPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1622 mg/kg
REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 23,714,1968
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >350 mg/kg
REFERENCE : IJSIDW Indian Journal of Pharmaceutical Sciences. (Kalina, Santa Cruz (East), Bombay 400 029, India) V.40(2)- 1978- Volume(issue)/page/year: 49,77,1987
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Safety Information
| Symbol | 
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xn:Harmful |
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| Risk Phrases | R22 |
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| Safety Phrases | S36-S28A |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | GD8490000 |
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| HS Code | 2916399090 |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
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