| CAS: | 150-13-0 |
| MF: | C7H7NO2 |
| MW: | 137.14 |
| EINECS: | 205-753-0 |
| Product Categories: | Amines;Aromatics;AMINOACID;Benzene derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Organic acids;Anilines (Building Blocks for Liquid Crystals);Benzoic Acids (Building Blocks for Liquid Crystals);Bifunctional Compounds (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials;Pharmaceutical intermediates;amine | carboxylic acid;NEXIUM;buildingblock;Intermediate;150-13-0;bc0001 |
| Mol File: | 150-13-0.mol |
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| 4-Aminobenzoic acid Chemical Properties |
| Melting point | 187-189 °C(lit.) |
| Boiling point | 251.96°C (rough estimate) |
| density | 1.374 g/mL at 25 °C(lit.) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5323 (estimate) |
| Fp | 250 °C |
| storage temp. | 2-8°C |
| solubility | 95% ethanol: soluble5%, clear to slightly hazy, colorless to yellow |
| pka | 2.50, 4.87(at 25℃) |
| form | Crystalline Powder |
| color | White to light yellow |
| Odor | Odorless |
| PH | 3.5 (5g/l, H2O, 20℃) |
| PH Range | 3.5 |
| Water Solubility | 4.7 g/L (20 ºC) |
| Sensitive | Air & Light Sensitive |
| Merck | 14,423 |
| BRN | 471605 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Combustible. Sensitive to light and air. May discolour on exposure to light. |
| InChIKey | ALYNCZNDIQEVRV-UHFFFAOYSA-N |
| LogP | 0.96 at 25℃ |
| CAS DataBase Reference | 150-13-0(CAS DataBase Reference) |
| IARC | 3 (Vol. 16, Sup 7) 1987 |
| NIST Chemistry Reference | p-Aminobenzoic acid(150-13-0) |
| EPA Substance Registry System | p-Aminobenzoic acid (150-13-0) |
| 4-Aminobenzoic acid Usage And Synthesis |
| Description | 4-Aminobenzoic acid (also known as para-aminobenzoic acid or PABA because the number 4 carbon in the benzene ring is also known as the para position) is an organic compound with the formula H2NC6H4CO2H. PABA is a white solid, although commercial samples can appear gray. It is slightly soluble in water. It consists of a benzene ring substituted with amino and a carboxyl groups. The compound occurs naturally. The potassium salt is used as a drug against fibrotic skin disorders, such as Peyronie's disease, under the trade name Potaba. PABA is also occasionally used in pill form by sufferers of irritable bowel syndrome to treat its associated gastrointestinal symptoms, and in nutritional epidemiological studies to assess the completeness of 24-hour urine collection for the determination of urinary sodium, potassium, or nitrogen levels. |
| Chemical Properties | colorless needle-like crystals. turns light yellow in the air or in light. Soluble in hot water, ether, ethyl acetate, ethanol and glacial acetic acid, insoluble in water, benzene, and insoluble in petroleum ether. |
| Originator | Pabalate,Robins,US,1949 |
| Uses | 4-aminobenzoic acid is an aminobenzoic acid isomer that combines with pteridine and glutamic acid to folic acid. The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in sunscreens. Also it is used as a component of some medicines e.g analgesic or anesthetic preparations sunscreen agents and bentiromide. |
| Definition | ChEBI: 4-aminobenzoic acid is an aminobenzoic acid in which the amino group is para to the carboxy group. It has a role as an Escherichia coli metabolite, a plant metabolite and an allergen. It derives from a benzoic acid. It is a conjugate acid of a 4-aminobenzoate. |
| Preparation | 4-Aminobenzoic acid synthesis method: add 38.0g of p-nitrobenzoic acid, 200mL of water, 20mL of tetrahydrofuran, 0.4g of sodium dodecyl sulfonate and 1.9g of Raney nickel to the autoclave, nitrogen replacement Three times, fill with hydrogen, adjust the pressure to 0.9±0.1MPa, adjust the temperature to 100±2°C, and keep the reaction under pressure for 4h to complete. After the reaction, the catalyst was recovered by filtration, left to stand for stratification, the water layer was directly applied mechanically, the tetrahydrofuran layer was distilled and recovered and applied mechanically, then 1.5 g of activated carbon was added to the 4-aminobenzoic acid mother liquor, and under nitrogen protection, heating and refluxing for decolorization for 20min, Filtration, cooling and crystallization of mother liquor, filtration, drying under vacuum at 80-85 °C to obtain 30.3 g of 4-aminobenzoic acid with a yield of 97.2%, a melting point of 187.1-187.6 °C, and a content of 100.2% (permanent stop titration method) . |
| Brand name | RVPaba Lipstick (ICN). |
| Therapeutic Function | Sunscreen agent, Antirickettsial |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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