Anti Cancer Pharmaceutical Intermediates Sorafenib Tosylate 475207-59-1
1. Product descroption:
Sorafenib tosylate ;anticancer drugs Pharmaceutical raw materials white powder; bodybuilding
Sorafenib tosylate
Chemical Name: 4 - {4 [3 - (4-chloro-3-trifluoromethyl-phenyl) ureide] phenoxy} pyridine-2-carboxamide p-toluenesulfonate
Product Alias: toluenesulfonic sorafenib mesylate Sorafenib Sorafenib p-toluenesulfonic
English name: Sorafenib tosylate
English Synonyms: Sorafenib (Nexavar)
CAS: 475207-59-1
Packing:As requirments
2.COA
Items of analysis |
Specification |
Results |
Description |
off-white powder |
Conforms |
Loss on drying |
NMT 1.0% |
0.7% |
Water content |
NMT 0.5% |
0.13% |
Single impurity |
NMT0.1% |
0.07% |
Total impurity |
NMT 0.5% |
0.29% |
Purity(HPLC) |
NLT 99.0% |
99.71% |
Conclusion |
Qualified |
3.More details:
Keywords: Sorafenib tosylate, sorafenib tosylate, mesylate Sorafenib, 475207-59-1
Molecular formula: C21H16ClF3N4O3.C7H8SO3
Molecular Weight: 637.03
Appearance: yellow or white crystalline powder
Melting point: 225-235 ºC
Loss on drying: Less than 0.5%
Heavy metals: Less than 10ppm
Total impurities: less than 1.0%
Content: 99%
Packing: 1kg / aluminum foil bag
Uses: toluenesulfonic Sorafenib is a novel multi-target anticancer drugs, can act simultaneously on tumor cells and tumor blood vessels. It has a dual anti-tumor effects: either by blocking the RAF / MEK / ERK-mediated cell signaling
Pathway directly inhibit the proliferation of tumor cells, but also by inhibiting VEGF and platelet-derived
Health factor (PDGF) receptors and block the formation of tumor angiogenesis, indirectly inhibit the growth of tumor cells.
Advantages:
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.
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