Quick detail
Vardenafil
CAS NO.: 224785-91-5
Molecular Formula: C23H32N6O4S
Product Name: Vardenafil
CAS NO.: 224785-91-5
Molecular Formula: C23H32N6O4S
Appearance: White to almost white crystalline powder, odorless, a little acerbity,
soluble in water, ethanol
Use: It is pharmaceutical raw material, indicated for the treatment of erectile dysfunction
Grade Pharmaceutical Grade
Assay 98%
Grade Pharmaceutical Grade
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Vardenafil
Usage : A selective phsphodiesterase type 5 (PDE5) inhibitor
A phsphodiesterase 5 inhibitor.
Vardenafil Description:
Vardenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, vardenafil works by increasing blood flow to the penis to help a man get and keep an erection.
This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Practice "safe sex" such as using latex condoms. Consult your doctor or pharmacist for more details.
How to use vardenafil
Read the Patient Information Leaflet provided by your pharmacist before you start taking vardenafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth as directed by your doctor, usually as needed. Take vardenafil, with or without food, about 1 hour before sexual activity. Do not take more than once daily. Doses should be taken at least 24 hours apart.
The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Precautions
Before taking vardenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure), stroke in the past 6 months, kidney disease (dialysis), liver disease, high or low blood pressure, a severe loss of body water (dehydration), penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease), history of painful/prolonged erection (priapism), conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma), eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION), bleeding disorders, active stomach ulcers.
Vardenafil COA:
Test Items |
Specification |
Test Results |
Description |
White or almost white crystalline powder |
White crystalline powder |
Melting Point |
191.0~193.0℃ |
192℃ |
Loss of drying |
<1.0% |
0.5% |
Heavy Metal |
<20ppm |
15ppm |
TLC |
Only one spot |
Only one spot |
Assay |
>99.5% |
99.91% |
Conclusion |
It complies with the USP 32. |
Important safety information:
- Vardenafil may cause dizziness, drowsiness, fainting, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use vardenafil with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Vardenafil may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Patients with heart problems who take vardenafil may be at increased risk for heart-related side effects, including heart attack or stroke. Symptoms of a heart attack may include chest, shoulder, neck, or jaw pain; numbness of an arm or leg; severe dizziness, headache, nausea, stomach pain, or vomiting; fainting; or vision changes. Symptoms of a stroke may include confusion; vision or speech changes; one-sided weakness; or fainting. Contact your doctor or seek medical attention right away if you experience these symptoms.
- Vardenafil may rarely cause a prolonged (more than 4 hours) or painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
- Vardenafil does not stop the spread of HIV or other sexually transmitted diseases (STDs) to others through sexual contact. Use barrier methods of birth control (eg, condoms) if you have HIV infection or an STD.
- Vardenafil will not prevent pregnancy. If your partner may become pregnant and you wish to avoid pregnancy, be sure to use an effective form of birth control.
- Vardenafil may uncommonly cause mild, temporary vision changes (eg, blurred vision, sensitivity to light, blue/green color tint to vision). Contact your doctor if vision changes persist or are severe.