1. Quick Details:
| Product name: |
Prednisone Acetate ;Prednisolone-21-acetate |
| CAS: |
125-10-0 |
| EC Number: |
200-134-1 |
| Molecular Formula: |
C23H28O6 |
| Molecular Weight: |
400.46 |
| Purity: |
99% min |
| Appearance: |
White or almost white crystalline powder, odorless, bitter taste. Insoluble in water, slightly soluble in ethanol, acetone and ethyl acetate |
| Density: |
1.28g/cm3 |
| Melting point: |
240-242º C (DEC. ) |
| Boiling point: |
582º C at 760 mmHg |
| FLash point: |
200.2º C |
| Usage: |
Biochemical studies, adrenal cortex hormones drugs, have anti-inflammatory, anti-allergy effects |
2. What is Prednisolone Acetate
Prednisolone Acetate is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. As a glucocorticoid receptor agonist, prednisolone acetate binds to specific intracellular glucocorticoid receptors, and causes the ligand-receptor complex to be translocated to the nucleus where it initiates the transcription of glucocorticoid-responsive genes such as various cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both potent mediators of inflammation. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations.
3. Prednisolone Acetate is used for :
This medication is used to treat certain eye conditions due to inflammation or injury. Prednisolone acetate works by relieving symptoms such as swelling, redness, and itching. It belongs to a class of drugs known as corticosteroids.
4. How to use prednisolone acetate ophthalmic :
Unless otherwise directed by your doctor, do not wear contact lenses while you are using this medicine. Sterilize contact lenses according to the manufacturer's directions, and check with your doctor before you begin using them again .
If your doctor does approve the wearing of contact lenses during treatment with this medication, remove the lenses before using the eye drops. The preservative in this product may be absorbed by contact lenses. Wait at least 15 minutes after each dose of the eye drop before wearing the lenses again .
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