Description:
2-Deoxy-D-glucose (2-DG) is a glucose analog that is structurally similar to glucose but lacks the hydroxyl group at the 2' position. This modification makes 2-DG unable to undergo further glycolysis, leading to various biological effects.
Properties:
Type: Glucose analog
Mechanism of Action: 2-DG interferes with glucose metabolism by competitively inhibiting glucose uptake and glycolysis in cells.
Uses:
Cancer Research:
2-DG has been extensively studied in cancer research due to its ability to selectively target cancer cells. By disrupting the energy production in cancer cells, 2-DG can induce cell death or sensitize cancer cells to other treatments like chemotherapy or radiation therapy.
Radioprotection:
Research has shown that 2-DG may have radioprotective effects by reducing the damage caused by ionizing radiation on normal tissues. This property makes it a potential candidate for protecting healthy tissues during radiation therapy.
Neuroprotection:
Studies have suggested that 2-DG may have neuroprotective effects by modulating energy metabolism in neurons. It has been investigated for its potential in treating neurodegenerative diseases and brain injuries.
Metabolic Disorders:
2-DG has also been studied in the context of metabolic disorders such as diabetes and obesity. By inhibiting glucose metabolism, it may help regulate blood sugar levels and improve metabolic parameters.
Antiviral Activity:
Recent research has explored the potential antiviral properties of 2-DG. It may interfere with viral replication by disrupting the energy metabolism of infected cells.
Precautions:
Dosage: Optimal dosages of 2-DG for different applications are still under investigation.
Side Effects: Common side effects may include gastrointestinal symptoms, hypoglycemia, and potential cytotoxic effects on normal cells.
Research: Further research is needed to fully understand the efficacy, safety, and potential applications of 2-DG in various conditions.
In conclusion, 2-Deoxy-D-glucose (2-DG) is a glucose analog that interferes with glucose metabolism in cells.
It has been studied for its potential applications in cancer research, radioprotection, neuroprotection, metabolic disorders, and antiviral activity. While 2-DG shows promise in various areas, more research is needed to determine its optimal dosages, potential side effects, and overall efficacy in clinical settings.
Product Forms: Injectable Solution, Oral Capsules/Tablets
Payment method: T/T in advance, Paypal, Western Union, L/C, etc.
Shipping ways: Courier, Air, Sea, Road
Storage Condition: Dry, dark, and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
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