| CAS: | 14338-32-0 |
| MF: | C6H7ClIN |
| MW: | 255.48 |
| EINECS: | 238-288-7 |
| Product Categories: | Coupling Reactions (Peptide Synthesis);Peptide Synthesis;Pyridinium Compounds;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry;C6Heterocyclic Building Blocks;Heterocyclic Compounds;Biochemistry;Condensation & Active Esterification;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridines |
| Mol File: | 14338-32-0.mol |
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| 2-Chloro-1-methylpyridinium iodide Chemical Properties |
| Melting point | 200 °C (dec.) (lit.) |
| density | 1.7949 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Crystalline Powder and/or Chunks |
| color | Yellow |
| Water Solubility | soluble |
| Sensitive | Moisture & Light Sensitive |
| Merck | 14,6301 |
| BRN | 3572320 |
| Exposure limits | ACGIH: TWA 0.01 ppm |
| InChIKey | ABFPKTQEQNICFT-UHFFFAOYSA-M |
| CAS DataBase Reference | 14338-32-0(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Chloro-1-methylpyridinium iodide (14338-32-0) |
| 2-Chloro-1-methylpyridinium iodide Usage And Synthesis |
| Chemical Properties | yellow crystalline solid |
| Uses | Condensation reagent for the synthesis of esters and ketenes, and for the kinetic resolution of carboxylic acids and alcohols. |
| Uses | 2-Chloro-1-methylpyridinium iodide is a reagent in a wide variety of dehydrative coupling reactions. It is also used to form carboxylate esters from acids and alcohols, carboxamides from acids and amines, lactones from -hydroxy acids and carbodiimides from N,N-disubstituted thioureas. |
| General Description | 2-Chloro-1-methylpyridinium iodide (Mukaiyama reagent), is a commonly used reagent in organic synthesis for the activation of the hydroxy group of alcohols and carboxylic acids. It is used to synthesize derivatives of esters, lactones, amides, lactams, and ketenes from the corresponding carboxylic acids. It is also used as an efficient coupling reagent in the synthesis of peptides because of its low toxicity, simple reaction conditions, and also less expensive than EDC. |
| Purification Methods | Purify it by dissolving in EtOH and adding dry Et2O. The solid is washed with Me2CO and dried at 20o/0.35mm. Store it in the dark. Attempted recrystallisation from Me2CO/EtOH/pet ether (b 40-60o) causes some exchange of the Cl substituent by I. The picrate has m 106-107o, and the perchlorate has m 212-213o. [Jones et al. J Am Chem Soc 111 1157 1989, UV and solvolysis: Barlin & Benbow J Chem Soc, Perkin Trans 2 790 1974, Beilstein 20/5 V 405.] |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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