Name | (1E,6E)-Bis(demethoxy)curcumin |
Description | (1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities. |
In vivo | Bisdemethoxycurcumin (BDMC) is a minor constituent (approximately 3%) of curcuminoids that has been shown to be more stable than the other two main curcuminoids, that is, curcumin and demthoxycurcumin. BDMC has anti-tumor effects exerted through a multimechanistic mode of action involving inhibition of cell proliferation, invasion and migration, metastasis and tumour growth, and induction of apoptotic death in cancer cells[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 31 mg/mL (100.54 mM)
|
Keywords | (E,E)-Curcumin III | Bisdemethoxycurcumin | inhibit | (E,E)-Didemethoxycurcumin | Inhibitor | Bis(demethoxy)curcumin | Apoptosis | Autophagy | (E,E)-Bisdemethoxycurcumin |
Inhibitors Related | Stavudine | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | Hydroxychloroquine | Guanidine hydrochloride | Tributyrin | Valproic Acid | Paeonol | Naringin | Gefitinib | Oleic acid |
Related Compound Libraries | Anti-Tumor Natural Product Library | Selected Plant-Sourced Compound Library | Natural Product Library | Antiparasitic Natural Product Library | Cosmetic Ingredient Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Food as Medicine Compound Library |