Name | (1E,6E)-Bis(demethoxy)curcumin |
Description | (1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities. |
In vivo | Bisdemethoxycurcumin (BDMC) is a minor constituent (approximately 3%) of curcuminoids that has been shown to be more stable than the other two main curcuminoids, that is, curcumin and demthoxycurcumin. BDMC has anti-tumor effects exerted through a multimechanistic mode of action involving inhibition of cell proliferation, invasion and migration, metastasis and tumour growth, and induction of apoptotic death in cancer cells[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 31 mg/mL (100.54 mM), Sonication is recommended.
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Keywords | Inhibitor | inhibit | Bisdemethoxycurcumin | Bis(demethoxy)curcumin | Autophagy | Apoptosis | (E,E)-Didemethoxycurcumin | (E,E)-Curcumin III | (E,E)-Bisdemethoxycurcumin |
Inhibitors Related | Stavudine | Aceglutamide | Cysteamine hydrochloride | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Tributyrin | Paeonol | Naringin | L-Ascorbic acid sodium salt | Alginic acid | Gefitinib |
Related Compound Libraries | Anti-Tumor Natural Product Library | Polyphenolic Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Natural Product Library for HTS | Cosmetic Ingredient Compound Library | Immunology/Inflammation Compound Library | Food as Medicine Compound Library | Anti-Cancer Active Compound Library |