Chinese name: 17-methyltestosterone
English name: 17-methyltestosterone
CAS: 58-18-4
EINECS: 200-366-3
Chemical formula: C20H30O2
Molecular weight: 302.46
InChI: InChI = 1 / C20H30O2 / c1-18-9-6-14 (21) 12-13 (18) the 4-5-15-16 (18), 7-10-19 (2) 17 (15) 7-10-19 (19, 3) 22 / h12, 15 to 17, 2 H, 4-11 h2, 1-3 h3 / t15 -, 16+,17+,18+,19+,20+/m1/s1
InChIKey: GCKMFJBGXUYNAG-HLXURNFRSA-N
Density: 1.0434 (rough estimate)
Melting point: 162-168°C(lit.)
Boiling point: 383.47°C (rough estimate)
Specific rotation: 79 º (c=1, alcohol)
Flash point: 5°C
Water solubility: 33.88mg/L(25 ºC)
Vapor pressure: 2.28E-09mmHg at 25°C
Solubility: H2O: ≤ 0.5mg/ml
Refractive index: 1.4800 (estimate)
Acidity coefficient: 15.13±0.60(Predicted)
Storage condition: 2-8°C
Appearance: Solid (photosensitive)
Color: white
Merck: 13,6148
BRN: 2057425
Physical and chemical properties: white crystalline powder, odorless, tasteless, hygroscopic, metamorphic in case of light. Mp161-166℃; Specific rotation [α]25D+69°-+75°(dioxane); Ethanol solution has maximum absorption at 240nm wavelength. Soluble in chloroform and dioxane, soluble in ethanol (1:5), acetone (1:10), methanol, slightly soluble in ether, insoluble in water, vegetable oil.
Function: Metestosterone can promote the development and maturity of male sexual organs and secondary sexual characteristics; Anti-estrogen, inhibit endometrial growth and ovarian and pituitary function; Promote protein synthesis and bone formation, stimulate bone marrow hematopoietic function, increase red blood cells and hemoglobin. It is clinically used in male hypogonadism, eunuchism, crypto disease, menorrhagia, uterine fibroids, endometriosis, senile osteoporosis, and aplastic anemia in children.