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Quick details of Propofol Powder
Product Name: Propofol
CAS Number: 2078-54-8
Appearance: light yellow liquids
Molecular formula: C12H18O
Molecular weight: 178.27
EINECS.No:218-206-6
melting point: 18 °C (lit.)
boiling point: 256 °C/764 mmHg (lit.)
density: 0.962 g/mL at 25 °C (lit.)
vapor pressure: 5.6 mm Hg ( 100 °C)
refractive index: n20/D 1.514(lit.)
flash point: >230 °F
solubility: Very slightly soluble in water, miscible with hexane and with methanol
water solublity: Very slightly soluble in water.
Acidity coefficient(Pka): pKa 11.10(H2O,t =20)(Approximate)
Storage condition: Inert atmosphere,Room Temperature
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What is Propofol used for?
Propofol injection is used to help you relax or sleep before and during surgery or other medical procedures. This medicine is an anesthetic and a sedative. Propofol may also be used to sedate coronavirus (COVID-19) patients who need mechanical ventilation in the intensive care unit (ICU).
Recommended dosages of Propofol
Most patients require 1.5-9mg/kg/h Propofol. The infusion may be supplemented by bolus administration of upto 1 mg/kg body weight. if a rapid increase of depth of sedation is required. In ASA III and IV patients lower doses may be required.
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