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Quick details of Cabergoline Powder
Product name: Cabergoline
appearance: white powder to white crystal solid
synonym: Dostinex(R);Cabaseril;(6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide;Cabergolina;N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-8g-ergoline-8-carboxamide;Dostinex;Cabergolinum; Cabaser; Cabergolinum [Latin]; Galastop(R); Galastop; Cabergolina [Spanish];
CAS Number: 81409-90-7
Appearance: White powder
Molecular weight: C26H37N5O2
Molecular formula: 451.6
EINECS.No: 200-419-0
melting point: 102-104°C
density: 1.156±0.06 g/cm³
solubility: DMSO: ≥10mg/mL
refractive index: 1.594
Acidity factor: 13.05±0.46 (PKa)
optical activity: [α]/D 61 to 68°, c = 0.5 in dichloromethane
storage condition: Store at +4ºC
usages : long-acting dopamine antagonists. For the treatment of hyperprolactinemia caused by primary or deviated pituitary tumors
What is Cabergoline used for?
Cabergoline is used to treat different types of medical problems that occur when too much of the hormone prolactin is produced. It can be used to treat certain menstrual problems, fertility problems in men and women, and pituitary prolactinomas (tumors of the pituitary gland).
The recommended dosage of DOSTINEX/Cabergoline Tablets for initiation of therapy is 0.25 mg twice a week. Dosage may be increased by 0.25 mg twice weekly up to a dosage of 1 mg twice a week according to the patient's serum prolactin level. Before initiating treatment, cardiovascular evaluation should be performed and echocardiography should be considered to assess for valvular disease.
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