Pharmaceutical Rasagiline Obesity Killer Raw Material CAS 136236-51-6 White Powder
Quick detail
Rasagiline |
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CAS No.: | 136236-51-6 |
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Synonyms: | (1R)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine; (R)-N-(2-Propynyl)-2,3-dihydroinden-1-amine; |
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Formula: | C12H13N |
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Exact Mass: | 171.10500 |
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Molecular Weight: | 171.23800 |
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PSA: | 12.03000 |
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LogP: | 2.28760 |
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Properties |
Density: | 1.05 g/cm3 |
Boiling Point: | 305.5ºC at 760 mmHg |
Flash Point: | 146.8ºC |
Refractive Index: | 1.606 |
More Information | MOQ: 10 Gram Available Packaging Detail: 25Kg / Fiber Drum Payment Terms: T/T, MoneyGram, Western Union and Bitcoin Delivery Method: HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post etc. Clearance Rate: 100% Custom Pass, Disguise Package and Safe Leading Time: at the very day after payment Delivery Time: 5-14 Working Days, Tracking Number Available Origin Place: Hubei Province, China Production Capacity: 500Kg/Month |
Rasagiline Description
Rasagiline (Azilect, TVP-1012, N-propargyl-1(R)-aminoindan) is an irreversible inhibitor of monoamine oxidase-B used as a monotherapy to treat symptoms in early Parkinson's disease or as an adjunct therapy in more advanced cases.
The racemic form of the drug was invented by Aspro Nicholas in the early 1979s. Moussa B.H. Youdim identified it as a potential drug for Parkinson's disease, and working with collaborators at Technion– Israel Institute of Technology in Israel and the drug company, Teva Pharmaceutical, identified the R-isomer as the active form of the drug.
Rasagiline Usage
Usage 1 | Treating Parkinson disease. |
Usage 2 | It may also be used for other conditions as determined by your doctor. |
Usage 3 | Rasagiline is a monoamine oxidase inhibitor (MAOI). Exactly how it works is not known. |
Usage 4 | It may help to increase a substance in the brain that affects motor function. |
Do NOT use rasagiline if:
you are allergic to any ingredient in rasagiline
you have moderate to severe liver problems
you are taking fluoxetine or have taken it within the past 5 weeks
you are taking selegiline or another MAOI (eg, phenelzine) or if you have taken any of these medicines within the past 14 days
you are taking cyclobenzaprine, dextromethorphan, meperidine, methadone, propoxyphene, a selective serotonin reuptake inhibitor (SSRI) (eg, paroxetine), a serotonin-norepinephrine reuptake inhibitor (SNRI) (eg, venlafaxine, duloxetine), St. John's wort, a tetracyclic antidepressant (eg, mirtazapine), tramadol, trazodone, a tricyclic antidepressant (eg, amitriptyline), or vilazodone
Contact your doctor or health care provider right away if any of these apply to you.
How should this medicine be used?
Use rasagiline as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take rasagiline by mouth with or without food.
Do not suddenly stop taking rasagiline without checking with your doctor. You may experience side effects such as fever or confusion.
If you miss a dose of rasagiline, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use rasagiline.
General Dosing Recommendations
When AZILECT is prescribed as monotherapy or as adjunct therapy in patients not taking levodopa, patients may start AZILECT at the recommended dose of 1 mg administered orally once daily.
In patients taking levodopa, with or without other PD drugs (e.g., dopamineagonist, amantadine, anticholinergics), the recommended initial dose of AZILECT is 0.5 mg once daily. If the patient tolerates the daily 0.5 mg dose, but a sufficient clinical response is not achieved, the dose may be increased to 1 mg once daily. When AZILECT is used in combination with levodopa, a reduction of the levodopa dose may be considered, based upon individual response.
General information:
If you have any questions about rasagiline, please talk with your doctor, pharmacist, or other health care provider.
Rasagiline is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.
Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take rasagiline or any other medicine.