Safe Oral Steroids L-Thyroxine T4 CAS 51-48-9 Pharmaceuticals Fat Loss Steroids
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Product Name | Levothyroxine Sodium (T4) |
Synonyms | L-Thyroxine sodium salt; sodium 4-o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosine; sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate hydrate (1:1:5); |
Molecular Formula | C15H11I4NNaO4 |
Molecular Weight | 799.8592 |
InChI | InChI=1/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1 |
CAS Registry Number | 55-03-8 |
EINECS | 200-221-4 |
Assay | 99% |
Appearance | White or white crystalline powder |
L-Thyroxine
Levothyroxine is used to treat an underactive thyroid (hypothyroidism). It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone levels can occur naturally or when the thyroid gland is injured by radiation/medications or removed by surgery.
aving enough thyroid hormone is important for maintaining normal mental and physical activity.
In children, having enough thyroid hormone is important for normal mental and physical development.
This medication is also used to treat other types of thyroid disorders (such as certain types of goiters, thyroid cancer).
This medication should not be used to treat infertility unless it is caused by low thyroid hormone levels.
Before taking L-Thyroxine
a thyroid disorder called thyrotoxicosis;
heart disease, coronary artery disease, or a history of blood clots;
diabetes (insulin or oral diabetes medication doses may need to be changed when you start taking levothyroxine);
anemia (lack of red blood cells);
osteoporosis, or low bone mineral density;
problems with your pituitary gland;
any food or drug allergies;
an untreated or uncontrolled adrenal gland disorder; or
if you have recently had a heart attack, or are having any symptoms of a heart attack (chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling).
L-Thyroxine Application:
1 . | T4/L-Thyroxine is pro-hormone, which your body converts into T3 at necessary rate only and thus it could be considered as much milder and safer drug than T3. |
2 . | L-Thyroxine is an excellent fat burner since your metabolism is greatly increased while being on it. You can afford to be a little sloppier on pre-contest dieting since it will still burn fat when you are taking in a lot of calories since your metabolism is going haywire. |
3 . | L-Thyroxine is widely used by bodybuilders and fitness addicts on precompetition cycle in order to get relief, also used by overweighed people to reduce weight. It increases metabolism and produces general stimulating effects. However, this substance should be used wisely. |
L-Thyroxine General Dosing Recommendations
When AZILECT is prescribed as monotherapy or as adjunct therapy in patients not taking levodopa, patients may start AZILECT at the recommended dose of 1 mg administered orally once daily.
In patients taking levodopa, with or without other PD drugs (e.g., dopamineagonist, amantadine, anticholinergics), the recommended initial dose of AZILECT is 0.5 mg once daily. If the patient tolerates the daily 0.5 mg dose, but a sufficient clinical response is not achieved, the dose may be increased to 1 mg once daily. When AZILECT is used in combination with levodopa, a reduction of the levodopa dose may be considered, based upon individual response.
The recommended doses of AZILECT should not be exceeded because of risk of hypertension [see WARNINGS AND PRECAUTIONS].
How should I take levothyroxine?
Take levothyroxine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Do not share this medication with another person, even if they have the same symptoms you have.
Levothyroxine works best if you take it on an empty stomach, at least 30 minutes before breakfast. Follow your doctor's dosing instructions and try to take the medicine at the same time each day.
It is very important to take the Levoxyl brand of levothyroxine with a full glass (8 ounces) of water. The Levoxyl tablet can dissolve very quickly and swell in the throat, possibly causing choking or gagging.
While using levothyroxine, you may need frequent medical tests.
Tell any doctor or dentist who treats you that you are using levothyroxine.
Store at room temperature away from moisture and heat.
It may take several weeks before your body starts to respond to levothyroxine. Keep using this medicine even if you feel well. You may need to use this medicine for the rest of your life to replace the thyroid hormone your body cannot produce.
L-Thyroxine Specifications:
Item | Specification | Result |
|
Appearance | An odorless, almost white or buff colored powder | pass |
|
Solubility | 1,Very slightly soluble in water | pass |
|
2,slightly soluble in alcohol | pass |
|
3,practically insoluble in most other organic solvents | pass |
|
4,disolves in diluted aqueous sodium hydroxide solutions | Pass |
|
Identification | a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. | pass |
|
b)The retention time of the major peak is confirm to the RS | pass |
|
Loss on Drying | Not more than 4.0% | 0.46% |
|
[a]20/D C=1 in 1M HCl/EtOH 1:4 | +18 ~ +22o | +20.9o |
|
Assay(HPLC) | Not less than 95.0% | 99.18% |
|
Levothyroxine sodium | Not more than 5.0% | 0.68% |
|
Conclusion: | Up to the Standard for Export |
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