| Common Name | Nitazoxanide |
|---|
| CAS Number | 55981-09-4 | Molecular Weight | 307.282 |
|---|
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A |
|---|
| Molecular Formula | C12H9N3O5S | Melting Point | 202ºC |
|---|
| MSDS | USA | Flash Point | N/A |
|---|
| Symbol | 
GHS07 | Signal Word | Warning |
|---|
Use of Nitazoxanide
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM).Target: OthersNitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. In vitro studies demonstrated much broader activity. Dr. Rossignol co-founded Romark Laboratories, with the goal of bringing nitazoxanide to market as an anti-parasitic drug. Initial studies in the USA were conducted in collaboration with Unimed Pharmaceuticals, Inc. (Marietta, GA) and focused on development of the drug for treatment of cryptosporidiosis in AIDS.The anti-protozoal activity of nitazoxanide is believed to be due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic energy metabolism. It has also been shown to have activity against influenza A virus in vitro. The mechanism appears to be by selectively blocking the maturation of the viral hemagglutinin at a stage preceding resistance to endoglycosidase H digestion. This impairs hemagglutinin intracellular trafficking and insertion of the protein into the host plasma membrane |
Shanghai JOA Yunao International trading Co.,Ltd.is a professional pharmaceutical company,located in Shijiazhuang City,shanghai Province,China.We are engaged in the manufacturer and supply of pharmaceutical intermediates,Phenacetin,Tianeptine sodium,Steroids powder, nootropics,Sarms,HGH, cosmetic ingredients, sex enhancer, plant extracts,etc.In the past years, our products have spread over more than 50 countries in the world.
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