Name: Terbinafine hydrochloride
Synonym: Lamisil Krem; Terbinafina [Spanish]; Terbinafien HCl; Terbinafine hydrochloride (Lamisil); (E)-N-(6, 6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine hydrochloride; Terbinafine hydrochloride (JAN); Terbinafinum [Latin]; SF 86-327 hydrochloride; (E)-N, 6, 6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride; Terbinnafine HCL; 1-Naphthalenemethanamine, N-(6, 6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-, monohydrochloride; Terbinafine HCL(DMF) and its intermediates; Lamisil (TN); Lamisil; N-[(2E)-6, 6-dimethyl-2-Hepten-4-yl]-N-methyl-1-naphthalenemethylamine hydrochloride;
CAS: 78628-80-5
EINECS: 245-385-8
Assay: 99%
M. F: C21H26ClN
M. W: 327.9
MP: 204-208 oC
BP: 417.9 oC at 760 mmHg
Density: 1.007g/cm3
Appearance: Crystalline Powder
Application: An orally active, antimycotic related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal.
Package: 25kg/drum
Standard: enterprise standard
Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue. Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in meth. soluble in ethanol, and slightly soluble in water.
It can be treated by Trichophyton (Red Trichophyton, Trichophyton rubrum, Trichophyton rubrum, Trichophyton rubrum and Trichophyton rubrum), Microsporum canis and Fusarium oxysporum Infection of skin, hair and nails. It can also treat various rickets (body lice, tinea, hand, foot and head lice, etc.) as well as skin yeast infections caused by Candida (Candida albicans, etc.), and hyperthyroidism caused by mold (for fungal infections )
Dosage: Tablets are for oral use, and external preparations such as solutions, gels, ointments are for skin application only. Oral, 0.25g per adult, once a day, depending on the degree of infection, general body and femoral hernia treatment is 2-4 weeks, hand and ankle are 2-6 weeks, skin candidiasis 2-4 weeks, Head lice for 4 weeks, hyperthyroidism for 6 weeks - 3 months. For external use, apply the appropriate amount to the affected area and its surroundings twice a day. The course of treatment depends on the degree of infection. The general body and femur are 2-4 weeks, and the hands, ankles and tinea versicolor are 4-6 weeks. The treatment time can be extended appropriately. Oral tablets of this product are not effective against tinea versicolor.
China
