Chinese name: 2-phenylacetamide
2 - phenylacetamide English name
Alias: 2-phenylacetamide
Phenyl ethyl amide
Phenylacetamide
CAS 103-81-1
EINECS 203-147-0
Chemical formula C8H9NO
The molecular weight of 135.163
Inchi inchi = 1 / C8H9NO/c9-8 (10) 6-7-4-6-7-4-5-7 / h1-5 h, 6 H2, (H2, 9, 10)
The density of 1.098 g/cm3
Melting point of 157-158 ℃
Boiling point 312.2°C at 760 mmHg
Flash point 142.6 ° C
Vapor pressure 0.000537mmHg at 25°C
The refractive index of 1.552
The physical and chemical properties are white flake crystals.
Melting point is 157 ℃
Boiling point 280~290℃ (decomposition)
Content: 99%
Soluble in hot water, ethanol, slightly soluble in cold water, ether and benzene.
As an intermediate in penicillin and phenobarbital.It is also used for the preparation of phenylacetic acid, fragrance and pesticide rodenticide.
The synthetic methodsPut styrene, sulfur, liquid ammonia and water into autoclave, react at 165℃, about 6.5MPa pressure, and then heat evaporation to remove hydrogen sulfide gas, add activated carbon decolorization, cooling, crystallization, filtration, drying to obtain phenylacetamide.This method can be improved for pipeline continuous production. Styrene and ammonium polysulfide solution are combined in accordance with the volume ratio of 1:2, through the high-pressure pipeline, the reaction temperature is 200℃, the reaction pressure is 6-7.8mpa, the reaction time is 1.5h.The post-treatment process of the reaction products is similar to the batch process of autoclave.Raw material consumption quota: styrene (99%) 1117kg/ T, sulphur (98.5%) 716kg/t, liquid ammonia (99%) 539kg/t, activated carbon 47kg/t.
Store in a cool, ventilated warehouse.Keep away from fire and heat.Should be stored separately with oxidant, acid, base, avoid mixing storage.Equip with the appropriate variety and quantity of fire fighting equipment.
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