99% Tretinoin / Retinoic Acid / Vitamin a Acid 302-79-4 With Factory Best Price
Production information :
Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia. It is also available as a generic. Its success in treating acute promyelocytic leukemia was a major breakthrough in the treatment of this type of leukemia.It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor gene to the promyelocytic leukemia gene.This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia.
Specifications
Particle Size | NLT 100% Through 80 mesh | conforms |
Loss on Drying | <2.0% | 0.47% |
Total Heavy Metals | ≤10ppm | conforms |
Arsenic | ≤3ppm | conforms |
Lead | ≤3ppm | conforms |
Total Plate Count | ≤1000cfu/g | conforms |
Total Yeast & Mold | ≤100cfu/g | conforms |
E.Coli | Negative | Negative |
Salmonella | Negative | Negative |
99% Tretinoin / Retinoic Acid / Vitamin a Acid 302-79-4 With Factory Best Price
China
