Product name | NICOTINAMIDE ADENINE DINUCLEOTIDE; NAD+; β-NAD |
Molecular Formula | C21H27N7O14P2 |
CAS No. | 53-84-9 |
Quality Standard | 98% up, Food grade |
Appearance | White powder |
Items | Specifications | Results |
Appearance | White Powder | Complies |
Solubility | Soluble in water | Complies |
ε at 260nm and pH 7.5 | (18.0±1.0) ×l03L/mole/cm | 17.8×l03L/mole/cm |
ε when reduced with alcohol dehydrogenase at 340nm and pH 10 | (6.3±0.2) ×l03L/mole/cm | 6.4×l03L/mole/cm |
Ratio at pH 7.5 |
A250/A260 | 0.83±0.03 | 0.83 |
A280/A260 | 0.21±0.02 | 0.20 |
Ratio when reduced with alcohol dehydrogenase at pH 10 |
A340/A260 | 0.43±0.01 | 0.43 |
Water(by K.F) | ≤10% | 3.5% |
Totalbacterial count | ≤300CFU/G | Complies |
Content | ≥90% | 92.3% |
Purity (byHPLC) | ≥ 95% | 98.02% |
Conclusion: | The product conforms to theaboverequirements. |
Storage: | Keep dry and away from light, storage at -20℃. |
Usage
Nicotinamide adenine dinucleotide (NAD+) plays a critical role in various biological processes and offers several advantages:
1. Energy Production: NAD+ is a key coenzyme involved in cellular metabolism, particularly in the production of adenosine triphosphate (ATP), the primary energy currency of cells. It participates in redox reactions in the mitochondria, facilitating the conversion of nutrients into energy.
2. Cellular Repair and Longevity: NAD+ is crucial for DNA repair mechanisms, helping to maintain genomic stability. It also activates sirtuins, a class of proteins linked to longevity and regulating cellular processes like DNA repair, apoptosis (cell death), and stress resistance.
3. Supporting Enzymatic Reactions: NAD+ acts as a cofactor for various enzymes, including those involved in cellular signaling, metabolism, and antioxidant defenses. It participates in hundreds of enzymatic reactions throughout the body.
4. Regulation of Circadian Rhythms: NAD+ levels have been associated with regulating the body's circadian rhythms, influencing the sleep-wake cycle and overall metabolic health.
5. Neuroprotection: NAD+ is involved in neuronal health and has shown potential in protecting against age-related neurodegenerative diseases like Alzheimer's and Parkinson's disease.
6. Anti-aging Properties: NAD+ precursors, like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), have gained attention for their potential to boost NAD+ levels, leading to claims of anti-aging benefits. Studies in animals have shown promise in improving healthspan and mitigating age-related decline.
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