Baclofen, also known as beconfen, becrofen and liluxing, is a drug with the names of Jishu, liolaisu and chlorophenylbutyric acid γ- A derivative of aminobutyric acid, an antispasmodic drug, is a skeletal muscle relaxant and sedative acting on the brain and spinal cord of the central nervous system. It inhibits the release of excitatory amino acids such as glutamic acid and aspartic acid by stimulating receptors, thus inhibiting the transmission of monosynaptic and polysynaptic reflex in the brain and spinal cord of the central nervous system, thus playing a role in relieving chemical Book spasm. It has been used in the treatment of muscle spasm since the mid-1960s. Recent studies have also found that this product can significantly reduce gastroesophageal reflux and improve its symptoms, effectively relieve the symptoms of dystonia in children, and treat the voiding dysfunction after central intractable spinal cord injury. In addition, the clinical application of intrathecal injection therapy can further improve the clinical efficacy, adjust the drug dosage at any time and stabilize the therapeutic effect.
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