CAS: 56-12-2
MF: C4H9NO2
MW: 103.12
EINECS: 200-258-6
Melting point 195 °C (dec.)(lit.)
Boiling point 248.0±23.0 °C(Predicted)
density 1.2300 (estimate)
FEMA 4288 | 4-AMINOBUTYRIC ACID
refractive index 1.4650 (estimate)
storage temp. Store at RT.
4-Aminobutyric acid (GABA) is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. Although chemically it is an amino acid, GABA is rarely referred to as such in the scientific or medical communities, because the term "amino acid," used without a qualifier, conventionally refers to the alpha amino acids, which GABA is not, nor is it ever incorporated into a protein. In spastic diplegia in humans, GABA absorption becomes impaired by nerves damaged from the condition's upper motor neuron lesion, which leads to hypertonia of the muscles signaled by those nerves that can no longer absorb GABA.