Product Information
Product name | γ-aminobutyric acid ; Gamma aminobutyric acid ; GABA ; 4-aminobutyricaeid;4-AB |
CAS No. | 56-12-2 |
Molecular Formula | C4H9NO2 |
Molecular Weight | 103.1 |
Quality Standard | 99% up, Food Grade |
Appearance | White powder |
Usage
γ-aminobutyric acid (Gamma-aminobutyric acid, GABA) is a non-protein amino acid, which is widely found in vertebrates, plants and microorganisms.
There are currently three production methods for GABA: chemical synthesis, plant enrichment, and biotransformation.
The reaction conditions of chemical synthesis are relatively severe, and there are chemical residues. Even if the purity is high, it is not a natural product, and is mainly used in the chemical and pharmaceutical fields.
The plant enrichment method uses the endogenous enzyme transformation of plant tissues to prepare GABA, but the GABA obtained by this method has low purity and is mostly used in the food industry. There are many GABA ingredients made from rice germ or germinated brown rice on the market to produce functional foods with functions of relieving fatigue, assisting in lowering blood pressure, and improving sleep.
The early research of the biotransformation method used Escherichia coli as the production strain. During the fermentation and culture process, the decarboxylation of glutamate decarboxylase was used to convert L-glutamic acid into GABA, and the pure GABA product was obtained after separation and purification. With the continuous development of biotechnology, some strains that also contain glutamate decarboxylase, such as yeast and lactic acid bacteria, have gradually replaced E. coli, thereby obtaining safer products.
Our GABA is fermented with our own research and development enzyme, and the purity is able to over 99%.
Function of γ-aminobutyric acid
γ-aminobutyric acid (GABA) has long been considered to be related to various stress and defense systems of plants. GABA increases as plants are stimulated, and is considered to be an effective mechanism in plants that responds to various external changes, internal stimuli, and ionic environment factors such as pH, temperature, and external natural enemies. GABA can also regulate the internal environment of plants, such as antioxidant, ripening, and preservation of plants. In recent years, GABA has also been found in plants as a signal molecule to transmit expanded information in plants. GABA has been found in soybeans, Arabidopsis, jasmine, strawberries and other plants one after another. Low concentration of GABA helps plant growth and development, while high concentration will have the opposite effect.
GABA is the most important inhibitory neurotransmitter in the central nervous system of mammals. It participates in a variety of physiological activities in the body. It has anti-anxiety, lowering blood pressure, improving liver and kidney function, accelerating alcohol metabolism, promoting brain vitality, and preventing skin aging.
COA of γ-aminobutyric acid
TEST | SPECIFICATION | RESULTS |
Appearance | White crystalline powder | Conforms |
Solution clarification | 1g sample is dissolved in 10ml water, solution should be clarified. | Conforms |
Assay (on dry basis) | ≥ 99.0% | 99.35% |
Melting point | 196。C - 203。C | 197.5。C - 197.9。C |
Heavy metal | ≤ 10 ppm | Conforms |
Residue Ignition | ≤0.5% | 0.36% |
Chloride(Q) | ≤0.10% | Conforms |
Bulk density (loose) | ≤ 40ppm | Conforms |
Tap density | 0.4-0.6/cm3 | 0.45/cm3 |
pH | 0.5-0.7/cm3 | 0.59/cm3 |
Microbiology | 6.5-7.5 | 7.31 |
Total plate count | ≤1000cfu/g | 500cfu/g |
Mold | ≤100 cfu/g | Conforms |
Escherichia Coli | Negative | Conforms |
Conclusion | Conforms with specification |