Collagen (Collagen) is the main component of the extracellular matrix and mainly presented in the form of insoluble fibrin. It is widely presented in animal bone, tendon, sheath muscles, ligaments, fascia, cartilage and skin, and is a extremely important protein in the connective tissue which accounting for 25% to 30% of the total protein of animal body. Its function are supporting organ and protecting the body. It is also the most important protein specie located in cellular matrix. There are many types of collagen; Collagen of bone and skin generally belong to type I collagen; Collagen of cartilage belongs to type II; Type III collagen is located in embryo skin; Collagen of cell basilar membrane belongs to type IV. Collagen has a unique triple helix structure which makes its molecular structure be very stable and make it have low immunogenicity and good biodegradability property. Collagen, as a natural biological resource, has a unique biocompatible and biodegradable property which cannot be matched by any synthetic polymer material today. In addition, it has other features such as hig
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