Clindamycin

Product Name: Clindamycin

CAS: 18323-44-9

MF: C18H33ClN2O5S

MW: 424.98

EINECS: 242-209-1

Overview

Clindamycin belongs to the lincomycin class of antibacterial drugs, and is a derivative of lincomycin. Its antibacterial activity is 4 to 8 times stronger than that of lincomycin. This drug acts on the 50s subunit of the ribosome of sensitive bacteria to prevent the elongation of the peptide chain and inhibit the protein synthesis of bacterial cells to play an antibacterial effect.

Traits

The hydrochloride salt is a white crystalline powder, odorless, and bitter in taste. It is very soluble in water, slightly soluble in ethanol, soluble in methanol, and almost insoluble in chloroform or acetone. The pH of the 10% aqueous solution is 3.0 to 5.5. Phosphate is a white or almost white crystalline powder, with hygroscopicity, odorless, and bitter taste. Easily soluble in water, slightly soluble in absolute ethanol, very slightly soluble in acetone, insoluble in ether and chloroform. The pH of 1% aqueous solution is 3.0-4.5.