Melting point 81-82°C
Boiling point 469.7±55.0 °C(Predicted)
Density 1.08±0.1 g/cm3(Predicted)
Storage conditions Store at RT
Solubility DMSO: soluble40mg/mL
Uses: third generation aromatase inhibitors. It is used to treat postmenopausal patients with advanced breast cancer.
Purpose: to treat breast cancer.
Application: the third generation aromatase inhibitor. It is used to treat postmenopausal patients with advanced breast cancer. A potent and selective triazole aromatase inhibitor, it can inhibit the aromatase dependent on cytochrome P-450 and block the biosynthesis of estrogen, which is the main factor to stimulate the growth of breast cancer cells. Treatment of breast cancer, especially for those with hormone adjuvant therapy after recurrence of postmenopausal women with advanced breast cancer.
China
