henoxymethylpenicillin, commonly known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It is a penicillin that is orally active. It is less active than benzylpenicillin (penicillin G) against Gram-negative bacteria. Phenoxymethylpenicillin is more acid-stable than benzylpenicillin, which allows it to be given orally. It exerts a bactericidal action against penicillin-sensitive microorganisms during the stage of active multiplication. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan. It is not active against beta-lactamase-producing bacteria, which include many strains of Staphylococci.
Phenoxymethylpenicillin has a range of antimicrobial activity against Gram-positive bacteria that is similar to that of benzylpenicillin and a similar mode of action, but it is substantially less active than benzylpenicillin against Gram-negative bacteria.
Chemical Name | phenoxymethylpenicillin potassium |
---|
Synonyms | Penicillin V potassium salt;Penicillin V potassium;Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt;Phenoxymethylpenicillin potassium; |
---|
CAS No. | 132-98-9 |
---|
Molecular Formula | C16H17KN2O5S |
---|
Molecular Weight | 388.48000 |
---|
PSA | 124.07000 |
---|
LogP | -0.30880 |
---|