sarM s4 Andarine Powder for Muscle Wasting CAS 401900-40-1
What Is Andarine?
Andarine, also known as S-4, S-40503, or 8, is a SARM developed with the aim of treating osteoporosis and muscle wasting.
SARMs (selective androgen receptor modulators) are drugs that bind to the androgen receptor (AR), which is the main site of action of the hormone testosteron.
In the early days, Andarine was described as the ideal SARM due to high oral bioavailability and great muscle- and bone-building effects (studied in animals) .
Phase I human trials with this drug have reportedly been successful but no studies have been published. However, further development of the drug was abandoned in favor of Ostarine, another SARM with a similar structure, also known as S-22.
Andarine (S-4) Description:
Synonyms: S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide;N-[4-Nitro-3-(trifluoromethyl)phenyl]-(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methylpropanamide;(2R)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide;Andarine;sarM s4
CAS: 401900-40-1
MF: C19H18F3N3O6
MW: 441.36
Chemical Properties:Pale Yellow Solid
Assay:98%
Usage:It is a potent and tissue-selective androgen receptor modulator (SARM)
Packing:foil bag or as required
Andarine (S-4) Usage:
1) May Increase Muscle Mass
This drug was developed to prevent muscle wasting, and animal studies do indeed show that Andarine improves muscle growth and strength in animals.
When given to castrated rats for 4 weeks, Andarine increased muscle weight as markedly as DHT (dihydrotestosterone). Moreover, unlike DHT, Andarine caused no prostate enlargement, which is a concern when taking steroids.
Twelve weeks after castration, Andarine was able to restore lean body (muscle) mass in rats .
2) May Increase Bone Strength and Combat Osteoporosis
Andarine increased bone mineral density and strength in both in castrated male rats and in female rats whose ovaries had been removed (this is a commonly used animal model of osteoporosis) .
Andarine may be especially beneficial in osteoporosis because, in addition to improving bone density, it also improves muscle strength, which may help reduce the risk of falls and fractures .
3) May Help Fat Loss
In female rats whose ovaries have been removed, apart from improving bone strength, Andarine also decreased body fat .
| Product Name | CAS NO. |
| MK-2866 (Ostarine, Enobosarm) | 401900-40-1 |
| GW501516 (Cardarine) | 317318-70-0 |
| LGD-4033 (Ligandrol) | 1165910-22-4 |
| RAD-140 (Testolone) | 1182367-47-0 |
| MK-677 (Ibutamoren) | 159752-10-0 |
| YK11 | 431579-34-9 |
| Andarine (S-4) | 401900-40-1 |
| SR9009 (Stenabolic) | 1379686-30-2 |
| Aicar | 2627-69-2 |
Ostarine,MK-2866, Enobosarm Enobosarm (Ostarine, MK-2866, GTx-024) - affects both muscle and bone, intended mainly for osteoporosis but also general treatment for andropause and reversing muscle sarcopenia in the elderly and for cachexia in cancer patients.
LGD-4033 pharmacological profile similar to that of enobosarm, Ostarine,MK-2866
MK-677, Ibutamoren, a secretagogue a secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly
Andarine (S-4) partial agonist, intended mainly for treatment of benign prostatic hypertrophy
GW-501516 It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease.
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