Product Name: Prilocaine
CAS: 721-50-6
MF: C13H20N2O
MW: 220.31
EINECS: 211-957-0
Melting point 37-38°
Boiling point bp0.1 159-162°
density 1.0117 (rough estimate)
refractive index nD20 1.5298
solubility Slightly soluble in water, very soluble in acetone and in ethanol (96 per cent).
form neat
pka pKa 7.32 or 7.89 (Uncertain)
Water Solubility 6.169g/L(25 ºC)
Chemical Properties It is a kind of needle-like crystals with the melting point being 37-38 ℃ and the boiling point being 159-162 ℃ (0.133kPa), and refractive index (nD20) being 1.5299. Its hydrochloride ([1786-81-8]) is a white crystalline powder. The Melting point is 167-168 ℃. It is soluble in water and ethanol, slightly soluble in chloroform. It has sour taste and bitter taste and is odorless.
Uses It is a kind of local anesthetic drug. The product has better efficacy than procaine and the local anesthesia intensity and speed being similar as lidocaine but with longer duration time and less toxicity as well as smaller accumulation effect. It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.
China
